The pancreas is a large gland in the abdomen. It secretes pancreatic juices into the small intestine to digest food, and secretes insulin into the bloodstream to regulate glucose levels. The pancreas is both an endocrine gland (releasing juices directly into the bloodstream) and an exocrine gland (releasing juices into ducts).

Microbiota in pancreatic health and disease: the next frontier in microbiome research

Diseases intrinsic to the pancreas such as pancreatitis, pancreatic cancer and type 1 diabetes mellitus impart substantial health and financial burdens on society but identification of novel mechanisms contributing to these pathologies are slow to emerge. A novel area of research suggests that pancreatic-specific disorders might be modulated by the gut microbiota, either through a local (direct pancreatic influence) or in a remote (nonpancreatic) fashion. In this Perspectives, we examine literature implicating microorganisms in diseases of the pancreas, specifically pancreatitis, type 1 diabetes mellitus and pancreatic ductal adenocarcinoma. We also discuss evidence of an inherent pancreatic microbiota and the influence of the intestinal microbiota as it relates to disease association and development. In doing so, we address pitfalls in the current literature and areas of investigation that are needed to advance a developing field of research that has clinical potential to reduce the societal burden of pancreatic diseases.

Pancreatic Disorders and Therapy is an open access peer reviewed journal within the field of medical sciences which publishes the eminent research in all the fields of medical and health sciences. 

Journal is having the Editorial Submission and Review Tracking System which provides the easy and feasible way to submit and track the manuscript by author and they can easily access about the review comments of their paper through this Editorial Submission and Review Tracking System. 

Types of manuscripts accepted by the Journal includes Research, Short communication, Review, Mini Review, Case Report, Case Series, Case Studies, Editorials, Thesis, Perspectives, Image Articles etc., 

Media Contact:

Robert Solomon

Managing Editor

Pancreatic Disorders & Therapy

E-mail: [email protected]

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