Cell Structure of Human cell recently discovered
Author Name: Keith Howell Category Name: Genetics and molecular Biology Description: Cell Structure of Human cell recently discovered The structure is a new type of protein complex that the cell uses to attach to its surroundings and proves to play a key part in cell division.The cells in a tissue are surrounded by a net-like structure called the extracellular matrix. To attach itself to the matrix the cells have receptor molecules on their surfaces, which control the assembly of large protein complexes inside them. These so-called adhesion complexes connect the outside to the cell interior and also signal to the... Read More
Death from cancer among intellectually disabled persons in Japan BACKGROUND: It is important to know the causes of death of intellectually disabled (ID) persons, but there have been few reports about them in Japan. MATERIALS AND METHODS: The numbers of deaths due to the diseases of the large classification of the ICD10 (Chapters 1-14) in 2005 in 5-year age categories were obtained from the vital statistics of Japan (excluding Chapters 15-22; i.e., external causes, etc.). The numbers of persons in 2005 in 5-year age categories were obtained from the census of Japan. Based on these data, the general mortality rates of the... 
Methods of inducing breast cancer in animal models: a systematic review Abstract Objective: Breast cancer is the second leading cause of death and the most common cancer in women. With respect to a large number of limitations in human studies, there is the need to develop experimental animal models. The purpose of this study was to investigate the development of breast cancer in laboratory animals. Materials and Methods: This systematic review was conducted based on the PRISMA checklist. Articles were extracted with selected keywords from the PubMed, SID, Springer, Medlib and SinceDirect databases without any language restrictions. 450 articles... 
Immunotherapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as activation immunotherapies, while immunotherapies that reduce or suppress are classified as suppression immunotherapies. In recent years, immunotherapy has become of great interest to researchers, clinicians and pharmaceutical companies, particularly in its promise to treat various forms of cancer. Immunomodulators: Immunomodulators are the active agents of immunotherapy. They are a diverse array of recombinant, synthetic, and natural preparations. Activation immunotherapies: Cancer: Cancer treatment used to be focused on killing or removing cancer... 
Cancer immunotherapy (sometimes called immuno-oncology) is the artificial stimulation of the immune system to treat cancer, improving on the immune system's natural ability to fight the disease. It is an application of the fundamental research of cancer immunology and a growing subspeciality of oncology. It exploits the fact that cancer cells often have tumor antigens, molecules on their surface that can be detected by the antibody proteins of the immune system, binding to them. The tumor antigens are often proteins or other macromolecules (e.g. carbohydrates). Normal antibodies bind to external pathogens, but the modified immunotherapy antibodies bind to the tumor... 
Immunoinformatics Approach-Multiple Peptides Vaccine Design from Glycoprotein E of Herpes Simplex Virus-3 Background: Herpes simplex virus (HSV) is a common human pathogen, causing infections of orofacial mucosal surfaces (HSV-1) and genital mucosal surfaces (HSV-2). Productive infection results in the formation of vesicular lesions in the mucosal epithelia, followed by spread of the virus to sensory neurons and establishment of a latent infection that may remain for the life of the host. Material and method: All sequences of glycoprotein E [Human herpes virus 3] were obtained from NCBI and these sequences were subjected to IEDB predicted tools, including B cell and... 
Advances in 3D Printing: 
Androgen Receptor as Prognostic Marker in Triple-Negative Breast Cancer Patients Purpose: The purpose of this study was to assess the prognostic impact of androgen receptor (AR) expression in patients with triple-negative breast cancer (TNBC). Methods/patients: 101 patients treated for primary TNBC without distant metastasis from 1999 to 2015 were identified from breast surgery database. Kaplan-Meier and Cox regression models evaluated disease-free survival (DFS) and overall survival (OS). Results: AR expression was positive (IHC>1%) in 40% of patients. OS at 36 and 60 months was 86% and 80% in AR-negative patients, and 100% and 96% in AR-positive patients (log rank test... 
Traditionally, 
Over the past two decades, medicine has been moving towards data-driven diagnoses and personalized therapies based on molecular information.1 Oncology is a prime example, with an ever-growing range of precision drugs designed to target specific driver mutations in cancer cells. However, while these drugs have provided some benefits, they have failed to transform survival in most tumor types. Frustratingly, identification of a particular genetic alteration is not enough to guarantee that a treatment will work. For example, drugs targeting the overactive V600E form of the signaling protein BRAF are effective in melanoma but have no activity in colorectal... 
Every person distills down to a script of DNA, and researchers are increasingly mining this genetic information to better inform care. Now, scientists have shown how RNA -- an offshoot of DNA -- is coming into its own as doctors sleuth out difficult-to-diagnose illnesses. In a new study in Nature Medicine, Stephen Montgomery, PhD, a Stanford associate professor of pathology and of genetics, shows why the transcriptome, the collection of RNA molecules in a cell, is a crucial clue to help decipher the source of some rare diseases. I had a chance to chat with Montgomery, getting his take on the value of transcriptomics,... 
Gene Mutations 
Journal of Genetic Syndromes & Gene Therapy Journal of 
Infection with hepatitis B virus (HBV) can be prevented by vaccination with HB surface antigen, which induces HBS specific antibodies and T cells. But the immunization status of workers and its relationship with occupational factors are not well documented. The goal is to examine the factors of risk and the immunization status against HBV among a population of workers. An assessment of the vaccination and the immunization status against HBV was conducted among a miscellaneous population of French workers, recruited from a medical occupational center, during a cross-sectional study. A representative sample of a population of 3000 workers enrolled, was... 
The conventional diagnosis of congenital rubella is a rare occurrence of an obvious maternal exposure, resulting in an infant born with obvious signs such as cataracts, deafness, microcephaly or congenital heart disease. In this case, a mother with no known symptom, sign or exposure of rubella gave birth to a male infant without complication. The infant had no notable abnormalities at birth. The boy had developmentally delayed, and between the ages of five and seven years was diagnosed with autism. At the age of ten years, an MRI of his brain evidenced a remote stroke. Careful examination of all medical... 
Medical Microbiology : A Guide to Microbial Infections Applied Microbiology: Open Access is a scholarly open access journal that deals with the study of Medical microbiology the study of the pathogenic microbes and the role of microbes in human illness, Pharmaceutical microbiology the study of microorganisms that are related to the production of antibiotics, enzymes, vitamins and vaccines, Industrial microbiology the exploitation of microbes for use in industrial processes It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue (volume... 
Latest update of Applied Microbiology LATEST RESEARCH NEWS ON SACCHAROMYCES CEREVISIAE Transcriptional Regulatory Networks in Saccharomyces cerevisiae We have determined how most of the transcriptional regulators encoded within the eukaryote Saccharomyces cerevisiaeassociate with genes across the genome in living cells. even as maps of metabolic networks describe the potential pathways which will be employed by a cell to accomplish metabolic processes, this network of regulator-gene interactions describes potential pathways yeast cells can use to manage global organic phenomenon programs. We use this information to spot network motifs, the only units of specification, and demonstrate that an automatic process can use... 
Journal of 
Bioethics reflects about much health related issues. Spiritual aspects involved in decision making are one of them. The inclusion of spiritual aspects in the Bioethics arena does not remove the secular character of bioethical reflection. In contrast, considering spiritual aspects may gave a broad and more complex understanding about motivations associated with the decisions that people make the Clinical Bioethics Committee of the Hospital de Clínicas de Porto Alegre, since 1993, had the mission to assist health professionals, patients and families in bioethical issues associated with the decision making process. Individual food choices can be conditioned by a great variety... 
Introduction: Emergency hospital admissions have been increasing in the UK over recent years [1,2]. With the predicted increase of about 53% in the proportion of people aged 65 and over in the UK between 2001 and 2013 [3] this trend is set to continue as some evidence suggest that the ageing population structure will be associated with increases in the number and frequency of emergency admissions [4]. In addition to its impact on health service resources, hospitalisation can lead to adverse consequences particularly for older people, including breakdown of formal and informal care, loss of social networks, and premature... 
Bacteriophages are viruses infecting bacteria; they are obligate intracellular parasites also require their own metabolism. Phages are excessively host-specific, capable only to infect certain classifications or even strains. Following their detection beginning in the 20th century, phages were expansively applied to treat diverse bacterial disorders in people and animals. At present, as the problem of antibiotic resistance serves ever more severe, several scientists also clinicians are observing again at bacteriophages as a therapeutic choice in the treatment of bacterial infections. The aim of this review is to consider the current evidence on the effects of bacteriophages for detection and control... 
The drug industry is one of the major players guiding the development of the medicines, biotechnology & pharmacology field. Drug discovery is the process by which drugs are discovered and designed. It is a process which aims at identifying a compound therapeutically useful in curing & treating disease. The process of drug discovery involves the identification of candidates, synthesis, characterization, screening & assays for therapeutic efficacy. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials. Developing a new drug is a tedious & expensive undertaking, despite promising... 
It is imperative to continue efforts to identify novel effective therapies that can assist in containing the spread of HIV. Recently acquired knowledge about the HIV entry process points to new strategies to block viral entry. For most HIV strains, the successful infection of their target cells is mainly dependent on the presence of the CD4 surface molecule, which serves as the primary virus receptor. The attachment of the viral envelope to this cellular CD4 receptor can be considered as an ideal target with multiple windows of opportunity for therapeutic intervention. Therefore, drugs that interfere with the CD4 receptor, and... 
Sociology is the field of sciences worried about the investigations of the public activity of human gatherings and people. Social examinations is a term used to portray the expansive investigation of different fields which includes past and current human conduct and connections. Research &Review: Journal of Social Science on revelation and development in different angles like Sociology, Geography, Economics, History, Cultural examinations, Ethnography, Sociolinguistics, Home science, Demography, Political sciences and so forth Surveys, Mini Reviews, Short Communications, Perspectives/Opinions, Letters, Short Note and Commentaries are acknowledged for production. This is an open access diary where one can discover logical research as... 
Teratogen: A teratogen is an agent that can disturb the development of the embryo or foetus Teratogenicity: It refers to the capacity of a drug to cause foetal abnormalities when administered to the pregnant mother. Drugs can affect the foetus at 3 stages: Fertilization and implantation: conception to 17 days—failure of pregnancy which often goes unnoticed. Organogenesis: 18 to 55 days of gestation, most vulnerable period, deformities are produced. Growth and development: 56 days onwards —developmental and functional abnormalities can occur Some Drugs and Its Teratogenic effects: Thalidomide: Thalidomide is widely used drug in 1950 and... 
Journal of Infectious Diseases & Preventive remedy is an open access, peer reviewed journal that publishes data on clinical, preventative, healing and social factors of Transmittable diseases. Journal of Infectious Diseases & Preventive medication focus on discovery and innovation in more than a few aspects of Infectious Disease Eradication, Neglected Diseases, Nosocomial Infection, Threshold Host Density, Microbiome Project, Pandemics, Mycology, Airborne Disease etc. Reviews, Mini Reviews, Short Communications, Case Reports, Perspectives/Opinions, Letters, Short Note and Commentaries are usual for publication. The Journal is correctly walking in the 7th Volume which covers a huge variety The Journal emphasizes high-level lookup and... 
Maturing is the on-going period of our lives not just for individuals likewise for living life forms. A few of us are intrigued to be sound and youthful during 70's and 80's of our life and even researchers working in this field are distinguishing exceptional courses in making new Anti-maturing creams, hostile to wrinkle creams, things important to maintain a strategic distance from to stay away from age related infections (making them to change the way of life) and to improve the psychological abilities. 
Dermatology centers around the analysis and treatment of conditions identified with skin, hair and nails. It additionally focuses on keeping up the wellbeing of your skin. Your skin is your body's biggest organ, which covers and secures your body. Anything that aggravates stops up or arouses your skin can cause side effects, for example, redness, growing, consuming and tingling. As of now in time, the whole world is experiencing skin related ailments like psoriasis, skin inflammation, dermatitis, rashes, skin inflammation, dandruff, skin contaminations, skin consumes, rosacea, Vitiligo, moles, skin labels and so on. As an outcome we need to offer... 
The microorganisms impact the endurance of each animal on the planet. Not every one of them causes sicknesses but rather larger part is totally innocuous. As Bacteria and Parasite are an extent of Microbiology, they are additionally the explanation behind existing diseases on the planet. On a very basic level, we need to understand that Disease is the point at which the contamination makes harm the person's essential capacities or frameworks. A contamination doesn't generally bring about sickness! They cause reactions as well as these moment living things are fundamental to the cycling of supplements in the eco-frameworks of the... 
Objective: Phytochemical constituents of herbal extracts has shown positive response of antioxidant activity. The purpose of the present study was to investigate the antioxidant activity of polyphenolic flavonoids in the ethanolic extract of stem of Nicotiana tabacum. Materials and Methods: Flavonoids contents were determined by both thin layer chromatography and aluminium chloride colorimetric method, where as phenolic content was determine by Folin-Ciocalteau method. Antioxidant activity was observed by determining the electron transfer (DPPH free radical scavenging), enzymatic biochemical assay (SOD and GST activity) and nonenzymatic biochemical assay (GSH content and lipid peroxidation). Results: Flavonoid and phenolic content were found... 
Immunotherapy: Open Access was congratulating its authors of most cited articles. The article entitled “
Cancer immunotherapy is a therapy used to treat cancer patients that involves or uses components of the immune system. Some cancer immunotherapies consist of antibodies that bind to, and inhibit the function of, proteins expressed by cancer cells. Other cancer immunotherapies include vaccines and T cell infusions. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards... 
Lyme Disease Lyme disease is the most common vector-borne disease in the United States. Lyme disease is caused by the bacterium Borrelia burgdorferi and rarely, Borrelia mayonii. It is transmitted to humans through the bite of infected blacklegged ticks. Typical symptoms include fever, headache, fatigue, and a characteristic skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system. Lyme disease is diagnosed based on symptoms, physical findings (e.g., rash), and the possibility of exposure to infected ticks. Laboratory testing is helpful if used correctly and performed with validated methods. Most cases... 
Meningioma with Remarkable Multiple Rosette Formation: A Diagnostically Difficult Case Lipomas are the most common soft tissue tumors that are encountered in clinical practice; however, the giant lipomas are extremely uncommon and are entities of great concern as they can often create a diagnostic dilemma and therapeutic challenge owing to their size, location and their close relationship with other benign and malignant mesenchymal neoplasms. These tumors are rarer in children as compared to the adults, with very few cases reported in the surgical literature worldwide. We herein present a case of a giant lipoma of the right shoulder in an... 
Lentinan Exerts its Anti-Inflammatory Activity by Suppressing TNFR1 Transfer to the Surface of Intestinal Epithelial Cells through Dectin-1 in an in vitro and mice model It has been reported that lentinan, β-1,3; 1,6-glucan derived from Lentinula edodes, suppresses intestinal inflammation and ameliorates symptoms of colitis. However, the mechanism of intestinal anti-inflammatory activity of lentinan and how it is recognized by intestinal epithelial cells remains largely unclear. The receptor for lentinan on intestinal epithelial cells was identified using an in vitro gut inflammation model consisting of Caco-2 and RAW264.7 cells. Colitis was induced in 7 to 8 week-old wild-type (WT) or... 
Tuberculosis Tuberculosis -- or TB, as it’s commonly called- is a contagious infection that usually attacks your lungs. It can spread to other parts of your body, like your brain and spine. A type of bacteria called Mycobacterium tuberculosis causes it. There are two forms of the disease: Latent TB: You have the germs in your body, but your immune system stops them from spreading. That means you don’t have any symptoms and you’re not contagious. But the infection is still alive in your body and can one day become active. If you’re at high risk for re-activation -- for... 
Food Borne Illness Foodborne illness (also foodborne disease and colloquially referred to as food poisoning) is any illness resulting from the spoilage of contaminated food, pathogenic bacteria, viruses, or parasites that contaminate food, as well as toxins such as poisonous mushrooms and various species of beans that have not been boiled for at least 10 minutes. Symptoms vary depending on the cause, and are described below in this article. A few broad generalizations can be made. For contaminants requiring an incubation period, symptoms may not manifest for hours to days, depending on the cause and on quantity of consumption. Longer... 
Immunotherapy: Open Access has published an article entitled “Bidirectional Regulation of A beta Aggregates: Focus on TherapeuticTargets for Alzheimer's Disease” in its volume 3 Issue 3 written by Ying Zhang, and Jiang-Tao Li. The article explains about Bidirectional Regulation of A beta Aggregates: Focus on TherapeuticTargets for Alzheimer's Disease. Commentary was as follows regarding Alzheimer disease (AD) is the most prevalent dementia of agingadult, characterized by progressive amyloid aggregates in the brain andimpairment in cognition and memory. In recent year, data fromclinical trials and mouse models showed that Aβ immunotherapy hadbrought new hopes to AD treatment, although undesirable... 
Journal of Cancer Research and Immuno-Oncology is one of the most promising and rapidly developing areas of cancer research. The journal focuses on the development of new therapies which improve human body’s immune response against cancer.Journal of Cancer Research and Immuno-Oncology covers a broad scope for the authors to make their valuable contributions in the area of cancer biology, tumor and stem cell biology, immunology, microenvironment and immunology, molecular and cellular pathobiology, immuno-oncology, prevention and epidemiology, therapeutics and targets. Journal of Cancer Research and Immuno-Oncology is focused on publishing articles on various areas of immunotherapy like cancer immunotherapy, tumor... 
Oral and Maxillofacial Surgery is a specialist branch of dentistry which specialize in disorders of the mouth, teeth, jaws and facial structures. It encompasses diagnosis, surgical and related management of various conditions such as impacted/embedded teeth misaligned jaws, facial pain and trauma, snoring/obstructive sleep apnea and oral cancer. Major complex surgery in OMFS is exciting, and often collaborative. It includes: craniofacial surgery for congenital problems, cancer and injuries involving the skull base, facial surgery for cancer, skin cancer surgery. Certain list of procedures undertaken by oral and maxillofacial surgeons include: surgical treatment of facial injuries, removal of head and neck... 
Journal of Cancer Research and Immuno-Oncology is a fast-developing open access journal in the field of cancer research. It focuses on becoming one of the best peer reviewed journal in the field of cancer research. Journal of Cancer Research and Immuno-Oncology covers a broad scope for the authors to make their valuable contributions in cancer biology, tumor, radiology, metastatis, cancer immunotherapy, oncology, radiation therapy etc This Journal provides a unique forum dedicated to scientists to express their research articles, review articles, case reports and short communications on any array of latest cancer research and Immuno-Oncology. The Journal of Cancer... 
Immunology is a branch of biomedical science which deals with an organism’s response towards an invading environmental factor. This process involves a complex interplay of invading particle and defence system of the host organism along with successive cascading molecular mechanism to eliminate the invading agent. Immunotherpay: Open Access is using Editorial Tracking System for quality in review process. Editorial Tracking is an online manuscript submission, review and tracking systems used by most of the best open access journals. Review processing is performed by the editorial board members of Immunotherpay: Open Access or outside experts; at least two independent reviewers... 
The 
Food Microbiology – main part to learn to be healthy Applied Microbiology: Open Access is a scholarly open access journal that deals with the study of Medical microbiology the study of the pathogenic microbes and the role of microbes in human illness, Pharmaceutical microbiology the study of microorganisms that are related to the production of antibiotics, enzymes, vitamins and vaccines, Industrial microbiology the exploitation of microbes for use in industrial processes It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue... 
Inviting for Articles : Applied Microbiology Applied Microbiology is a peer-reviewed Open Access Journal, encourages on-going international research and articles related to but not limited to Medical microbiology, pathogenic microbes, Pharmaceutical microbiology (antibiotics, enzymes, vitamins, vaccines) Industrial microbiology, Microbial biotechnology, Plant pathology, Veterinary, Food, Agricultural, Soil, Environmental Microbiology, etc. It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue in the form of Research, Reviews, Commentaries, Letter to Editor, Case Reports, Short Communication, Images, Conference Proceedings which will be published in... 
Genetic syndromes-New 2020 Issue Journal of 
Gene Mapping NLM ID: 101574143 Index Copernicus Value 2016: 84.15 The Journal of 
In 2014 the Advisory Committee on Immunization Practices (ACIP) approved a dose of 13-valent pneumococcal conjugate vaccine (PCV13) for all adults at age 65 years. This further complicated the pneumococcal vaccination schedule, which was already one of the most complicated schedules. This study documents simplified schedules that were considered and discarded by the pneumococcal working group before making the most recent recommendation. We examined the marginal cost-effectiveness of several simplified schedules for older adults (age 50+ years) when compared with current recommendations. Our primary outcome was the cost-effectiveness ratio of quality-adjusted life years to cost. We used a probabilistic model... 
The capacity of bacteria to resist against the ejects of an antibiotic is called antibiotic resistance. Antibiotic resistance is due to the change in bacteria by some approach that eliminates or reduces the efficiency of chemicals, drugs, or other agents designed for treatment against infections. The survival and continuously multiplication of bacteria causes more destruction in human body. A few years back, main focus of research was centered regarding gram-positive bacteria resistant. Currently, clinical microbiologists strongly are in view that multidrug-resistant gram-negative bacteria are the major risk for human health. The gram-negative bacteria resistance increasing faster than in gram-positive bacteria.... 
Diverse Diagnosis of a Single Sinonasal Mass and how was Mystery Solved Abstract Background: Although the nasal cavity and paranasal sinuses occupy a relatively small anatomical space, they are the site of origin of some of the more complex, histologically diverse group of tumours in the entire human body. Carcinomas of the nasal cavity and paranasal sinuses account for 0.2-0.8% of all malignant neoplasms and 3% of those occurring in the head and neck. Sinonasal undifferentiated carcinoma is a very rare tumour with fewer than 100 reported cases. Case report: In our case, a 50yr female came to the... 
Multifocal Angiosarcoma of the Scalp: Review of the Literature and Report of Two Cases Abstract Cutaneous angiosarcoma of the head and neck is a rare disease with a very difficult treatment. We report two cases of patients with cutaneous angiosarcoma of the scalp and a review of the literature. Both patients were female and their average age was 70.3 years. In the two cases, the clinical presentation of the angiosarcoma was a multifocal tumor of the scalp with bleeding and ulceration. One of the patients had regional lymph node metastasis and the other had lung metastasis. Both lesions received... 
The 
Our aim is to provide the surgeons, refractive surgeons, optometrists, opticians, young researchers, students, industrial delegates and anyone professionally involved in study of 
Journal of Cancer Research and Immuno-Oncology brings articles in all areas related to cancer immunotherapy, immunotherapy, tumor immunology, necrosis, nucleic acid research, immune suppression, immunosurveillance, tumor immunity, immunotherapies, metastatic cancer, immune system, chemotherapy, etc. Journal of Cancer Research and Immuno-Oncology is a fast-developing open access journal in the field of cancer research. It focuses on becoming one of the best peer reviewed journal in the field of cancer research. Journal of Cancer Research and Immuno-Oncology covers a broad scope for the authors to make their valuable contributions in cancer biology, tumor, radiology, metastatis, cancer immunotherapy, oncology, radiation therapy etc... 
Immunotherapy: Open Access has recently published an article entitled “Multiplex Immunohistochemistry: The Importance of Staining Order WhenProducing a Validated Protocol” in its volume 5 Issue 2 written by Jihad Syed, Jack Ashton, Jesuchristopher Joseph, Gemma N Jones, Christian Slater, Alan Sharpe,Garry Ashton, William Howat, Richard Byers, Helen K Angell from Institute of Cancer Sciences, University of Manchester, Manchester, UK and Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK. The article explains about the complexity of multifactorial diseases, such as cancer, poses significant challenges to the development of personalised therapies. Integrated digital histological analysis of tumoursprovides a better understanding of the... 
Teucrium (Lamiaceae) is a large and polymorphic genus distributed mainly in the Europe, North Africa and in the temperate parts of Asia. In Iran, 12 species are native. In this study, the anatomical features of the leaf and stem Teucrium polium are investigated. T. polium belonging to sect. Polium is a perennial herb growing on Lorestan province. The anatomical studies on T. polium revealed that the stem shares the general characteristics of the Labiatae family. The leaves clearly exhibit xeromorphy due to features such as the thick cuticle layer, thick outer epidermal cell wall, a high density of trichomes and... 
The seed morphology of six species of the genus Juncus L. (Juncaceae), involving wild annuals and perennials was studied in Northeast of Iran using Light and Scanning Electron Microscope (SEM). Seed morphology (light microscope) of the investigated species exhibits certain variations in shape, size and surface ornamentation. Results of SEM analysis reveals that there are different patterns of seed surface. Seed shape and surface structure exhibit some diversity among taxa indicating systematic significance in species differentiation. An identification key to the investigated taxa is provided based on seed characters in this research. he genus Juncus L. (Juncaceae) is a widely... 
Dengue fever has become a global concern as dengue infections are prevalent in the tropics and the subtropics, and can lead to a severe life-threatening illness. Currently, there is a widespread interest to search for vaccine or antiviral therapy to combat DENV infection. In this study, we have identified emetine dihydrochloride with potent antiviral activity against DENV infection. Emetine was also shown to inhibit DENV replication consistently in all the dengue serotypes. Experiments were designed to define the stage of viral replication cycle at which emetine blocked DENV infection. Emetine did not target the entry process of DENV into cells... 
HIV infection is a leading health problem across the entire world, including United States. Recent advances in medicine have led to a significant decline in mortality associated with HIV infection and hence increased life expectancy in HIV-infected individuals. Cardiovascular complications represent an increasingly important health concern in HIV-infected population especially after the introduction of anti-retroviral therapy. Numerous research studies have demonstrated the increased prevalence of cardiovascular disease in HIV infected individuals. The etiology of the preponderance of cardiovascular manifestations associated with HIV is still not well established. It may be attributed to virus itself, the effects of anti-retroviral medications; or... 
Chimeric antigen receptor T cell (CAR-T) therapy has shownsignificant efficacy in treating patients with refractory B-cellleukemia and lymphoma [1,2]. However, CAR-T therapy hasyielded less favorable results in treating patients with solidtumors such as pancreatic, ovarian or mesothelioma cancers[3-5]. One of the major obstacles in treating solid tumors withCAR-T is the scarcity of antigen that is uniformly expressed intumor cells such as CD19 in B cell hematologic malignancies[6,7]. Therefore, designing a CAR against an antigen that ishighly expressed in cancer cells but either has negligible orreduced expression in normal tissues to avoid off-tumor toxicityis extremely critical. Several CAR-T clinical trials in... 
Journal of Immunotherapy: Open access features rapid publication of articles on immunomodulators, lymphokines, antibodies, cells, and cell products in cancer biology and therapy. Laboratory and preclinical studies, as well as investigative clinical reports, are presented. The journal emphasizes basic mechanisms and methods for the rapid transfer of technology from the laboratory to the clinic. IMT contains full-length articles, review articles, and short communications. Instructions for authors are as follows: Manuscript important element properties Title: Title should be clear, meaningful and brief (no longer than 25 words). The abbreviations should not be used in the title. ... 
Developing Electronic-nose Technologies for Clinical Practice The development of relatively simple gas-sensing devices with sensor arrays capable of constructing molecular profiles of complex Volatile Organic Compound (VOC) metabolites from clinical samples, based on production of healthy or disease-specific digital signature patterns, may soon help to revolutionize diagnostic procedures in clinical practice. This mini-review summarizes the development of recent portable electronic-nose (e-nose) technologies as new diagnostic tools with the potential for accelerating clinical procedures to facilitate non-invasive early disease diagnoses, improving the speed and ac To know more about the article: https://www.longdom.org/medical-surgical-pathology/current-issue.html How we work: After submission, an acknowledgement with manuscript... 
Issues and Perspectives in Psoriasis Management Psoriasis is recognized as a chronic inflammatory autoimmune disease caused by genetics, the immune system and environmental factors with inherent aberrations in the skin in the form of either consistently excess proliferation of cellular constituents, particularly the epidermis, keratinocytes to hyperproliferate and perpetuate the disease process. Psoriasis varies in severity from small, localized patches to complete body coverage. These skin patches are typically red, dry, itchy and scaly. Humans lose five thousand million skin cells every day. How this colossal shedding process can occur without there being a break in the skin barrier is... 
Journal of Plant Biochemistry & Physiology is celebrating 7th Anniversary it’s been seven years we have started the Journal. The open access journal is published by Longdom who hosts around 350 open access peer-reviewed journals as well as organizes more than 100 International scientific Conferences. We are privileged to welcome 
The 
Our aim is to provide the surgeons, refractive surgeons, optometrists, opticians, young researchers, students, industrial delegates and anyone professionally involved in study of 
New approach to pain treatment in diseases of the pancreas One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic patients. In a recent study, a team at the Technical University of Munich (TUM) discovered the cause of this phenomenon for the first time: a particular neuroenzyme in the body is present in the nerves of the organ in high concentrations. In many cases only potent analgesics such as opiates are able to relieve the suffering of those affected. But... 
The pancreas is a large gland in the abdomen. It secretes pancreatic juices into the small intestine to digest food, and secretes insulin into the bloodstream to regulate glucose levels. The pancreas is both an endocrine gland (releasing juices directly into the bloodstream) and an exocrine gland (releasing juices into ducts). Microbiota in pancreatic health and disease: the next frontier in microbiome research Diseases intrinsic to the pancreas such as pancreatitis, pancreatic cancer and type 1 diabetes mellitus impart substantial health and financial burdens on society but identification of novel mechanisms contributing to these pathologies are... 
Trauma continues to remain the leading cause of morbidity and mortality in the developed countries. Hemorrhage is the second most common cause of death after trauma, only outnumbered by traumatic brain injury. Exsanguinating hemorrhage is the most common cause of mortality in the first hour of arrival to a trauma center and accounts for almost half of deaths in the first 24 h. In addition, about 20-40% of trauma deaths that occur after hospital admission usually involve massive hemorrhage, in which death is potentially preventable. Although the resuscitation protocols and management strategies for resuscitation of patients with exsanguinating hemorrhage have ... 
The Recent published article in the 
The very first published article in the 
A number of different approaches aimed at broadening the cross-protective ability of seasonal influenza vaccines are being explored today. Priming a seasonal vaccine with three administrations of DNA encoding H1 HA corresponding to the HA in the seasonal vaccine has been shown to confer protection against heterologous H1N1 influenza. Here we evaluated the heterosubtypic protection induced by a seasonal influenza vaccine when primed with H1 HA DNA and, in parallel, when given as a homologous prime/boost regimen. Balb/c mice were immunized three times with vaccine homologous H1 HA DNA prior to a boost with seasonal influenza vaccine (season 2009/2010; Northern... 
Neospora caninum, the parasite that causes neosporosis, is known worldwide as one of the main drivers of abortion in cattle herds, causing economic losses when raising livestock. Parasitic infection and transmission among animals are difficult to combat, and both diagnostics and controls must be applied to reduce the spread of the pathogen. For control, herd vaccinations represent an alternative, but the current lack of a safe and effective vaccine prevents this method. The parasite has a significant array of structural proteins that assist in the process of infection; surface antigens (SAGs), microneme proteins (MICs), dense granule antigens (GRAs) and rhoptria... 
During the course of my career as a child neurologist and faculty member of the Johns Hopkins Berman Bioethics Institute, I have developed a familiarity with the various moral philosophies: Utilitarian, Aristotelian, Kantian, but have found that they rarely enter my thinking or language as I make difficult clinical decisions at the bedside. They seem much like the field of biochemistry, useful as background, but rarely of use at the bedside. I am clearly a Utilitarian clinician striving to produce the greatest good for the greatest number, but that number is always constrained to the individual family and child at... 
The Journal 
Background: In recent years, 
Ovarian Cancer - The Silent Killer Abstract Ovarian cancer is heterogeneous, multigenetic and epigenetic abnormalities and lethal among all other gynecological women malignancies amongst women. Moreover, ovarian cancer has a distinct biology and behavior at cellular and molecular level. According to National Cancer Institute’s Surveillance, Epidemiology and End Result Program Report in 2017 the new case of ovarian cancer exacerbated to 22.4% from 11.7% in 2014. The Therapeutics use of cancer therapies has been restricted due to its nonspecific and dose limiting cellular toxicity and development of multidrug resistance. To overcome the restriction various biotechnological therapies and drug delivery system... 
Journal of Tumor Research: A strategy document from the NCRI Brain Tumor CSG Abstract The National Cancer Research Institute (NCRI) is a partnership of charity and government research funders whose purpose is to improve health and quality of life by accelerating progress in cancer-related research through collaboration. Under this umbrella, the NCRI Brain Tumor Clinical Studies Group is focused on improving clinical outcomes for adult patients with brain and central nervous system tumors, including those with brain metastasis from other primary sites. This document discusses the current state of clinical brain tumor research in the United Kingdom and the challenges... 
View on Food microbes -Applied Microbiology: Open Access Applied Microbiology: Open Access is a scholarly open access journal that deals with the study of Medical microbiology the study of the pathogenic microbes and the role of microbes in human illness, Pharmaceutical microbiology the study of microorganisms that are related to the production of antibiotics, enzymes, vitamins and vaccines, Industrial microbiology the exploitation of microbes for use in industrial processes It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue in the... 
Instructions for Authors for Submission Manuscripts :Applied Microbiology Applied Microbiology is a peer-reviewed Open Access Journal, encourages on-going international research and articles related to but not limited to Medical microbiology, pathogenic microbes, Pharmaceutical microbiology (antibiotics, enzymes, vitamins, vaccines) Industrial microbiology, Microbial biotechnology, Plant pathology, Veterinary, Food, Agricultural, Soil, Environmental Microbiology, etc. It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue in the form of Research, Reviews, Commentaries, Letter to Editor, Case Reports, Short Communication, Images, Conference Proceedings which will be... 
On behalf of the Journal, as Editor-in-Chief, it is my distinct honour and privilege to welcome you to the Journal of Theoretical and Computational Science. The 
Perturbation of bacterial microflora of the gastrointestinal (GI) tract may play an important role in the pathophysiology of some GI disorders. 
Gene Expression - RNA to protein 
Gene Syndrome 
Commentary on “Gallbladder Cancer: South American Experience When I was invited by Dr. Ghassan Abou-Alfa to write an article about the South American experience in gallbladder cancer (GC) I felt enthusiasm. It was an opportunity to make a contribution to this public health problem. GC is among the leading causes of death from cancer in women in many Western areas in my country Argentina and in South America. Based on their daily practice experience many health workers in Salta, the province where I live at the northwest of Argentina, know that GC is a local public health problem. So,... 
MicroRNAs in Skin Biology: Biogenesis, Regulations and Functions in Homeostasis and Diseases The progression in science gives novel and deeper understandings of human beings organisms. The Human Genome Project uncovered about 20,500 human genes. More recently, non-coding RNAs saw the light and gained researchers interest. Among the different subsets of these non-coding RNAs, microRNAs were identified as 18-25 nucleotides long and have been shown to play critical regulatory roles in a wide range of cellular processes. Emerging studies highlighted the importance of miRNAs in health and in disease. Ten years ago, the role of miRNAs in cutaneous system has been... 
ARF is common in the setting of critical illness and is correlated with a high risk of mortality. The aim of this study was to determine the risk factors and short term outcome of Acute Renal Failure (ARF) in intensive care unit (ICU). This study was designed as an analytic cross-sectional study. First, 201 Patients who hospitalized in the ICU enrolled in this study. ARF was defined as a plasma creatinine levels according to Acute Kidney Injury Network (AKIN) criteria.The assessed risk factors of ARF were age, gender, Cause of hospitalization in the ICU, Imaging with Contrast agents, mechanical ventilation,... 
Having fear and anxiety is necessary in any animal, for their survival. In humans, fear cause they behave reliable and safe. The nature of anxieties and fears changes with increasing age and learning knowledge. Fear or phobia of animals such as snakes, Zoophobia, Herpetophobia, scorpions, arachnids, Archnophobia, insects and Entomophobia is common. Entomophobia is an unusual fear of insects that may cause psychological problems in individuals at critical situation, which needs effective treatment. If these feelings of fear and anxiety be stable, may affect people's mental health. Anxiety caused by fear, will have long-term effects. Fear of arachnids and insects... 
Full length Ebolavirus glycoprotein (GP) intersperses the outer most lipid membrane to form spikes, where it mediates virus-host cell interaction. A secretory form of GP (sGP) is also produced by all 5 known Ebolavirus species. These attributes make GP an ideal target for research and development (R and D) of Ebolavirus and possibly pan-filovirus targeted Rapid Diagnostic Tests (RDTs), bio-therapeutics and vaccines. Prior cloning of recombinant Zaire ebolavirus (EBOV) GP has majorly used insect (baculovirus ) expression systems. We report the cloning, expression and purification of the full length and extracellular domain (ECD) forms of recombinant EBOV GP in mammalian cell-lines. 2034 and 1956 base-pair (bp) coding... 
A recently created apparatus to break down the cell and sub-atomic profiles of synovial tissue and fringe blood may help open signs about rheumatoid joint inflammation and lead to better treatments. Rheumatoid joint pain (RA) is an interminable ailment that causes torment, firmness, expanding, and constraint in the movement and capacity of different joints. In spite of the fact that joints are the chief body parts influenced by RA, aggravation can create in different organs too. An expected 1.3 million Americans have RA, and the illness regularly influences ladies twice as frequently as men. APS is a fundamental immune system... 
Clinical-Therapeutic Importance of Bioimpedance in Patients with Lymphedema Introduction: Lymphedema is characterized by abnormal accumulation of macromolecules and soft tissue fluids. Bioimpedance is a method that measures intra- and extracellular volumes by body segment, and has been currently used in lymphedema. Objective: The objective of this study was to conduct a systematic review of the clinical-therapeutic importance of bioimpedance in patients with lymphedema. Methodology: The present work consisted of a literature review. The systematic review made it possible to know and transcribe important subjects on clinical and therapeutic bioimpedance in patients with lymphedema. The work was carried out from September... 
Parathyroid Carcinoma has a PD-L1 Expression, and Share with Atypical Neoplasms an Abundant Intratumoral Macrophagic Aim: The aim of this study was characterized programmed death-ligand 1 (PD-L1) expression and tumoralinfiltrating lymphocytes (TILs) in parathyroid carcinoma (PC) and atypical parathyroid neoplasms (ANs). Methods: Our tissue samples constitute 30 parathyroid tumors (17 PC and 13 ANs) which were available from a prospectively collected database at the University of Texas M.D Anderson Cancer Center from 1996 to 2016. All samples were meticulously reviewed utilizing the current World Health Organization histopathological criteria. Each of the samples was immunohistochemically analysed for PD-L1, CD3, CD8... 
On behalf of the 
The beneficial role and efficacy of Tranexamic Acid in reducing perioperative blood loss and blood transfusion equirements in spine surgery is being established. Tranexamic Acid is an anti fibrinolytic agent traditionally used tolessen perioperative blood loss. Tranexamic Acid can be administered orally, intramuscularly, intravenously ortopically. Tranexamic Acid studies in spine surgery have limited patient enrolment. Most of the reported studies have mixed results and difficult to interpret. The efficacy of anti fibrinolytic agents is evident in a wide variety of surgicalprocedures: liver transplantation, obstetrics and gynaecology, trauma and orthopaedic surgical procedures. The effect of Tranexamic Acid on the occurrence of... 
Gene Expression Visakhapatnam, 29-11-2019 On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Genetic Syndromes & Gene Therapy. The Journal of 
Evolutionary Trends in Gene Visakhapatnam, 29-11-2019 The Journal of 
Tumor Genomics 
Bone Tumors Bone tumors grow when cells in the bone divide without control, forming a mass of tissue. Most bone tumors are benign, which means they are not cancer and do not spread to other areas of the body. But they may still weaken bone and lead to broken bones or cause other problems. Bone cancer destroys normal bone tissue. It may start in the bone or spread from other parts of the body (called metastasis). Benign Bone Tumors Benign tumors are more common than tumors caused by cancer. These are a few common types of benign bone tumors: Osteochondroma... 
The team “
The Journal, 
Racial Differences in Hospital Stays among Patients Undergoing Craniotomy for Tumour Resection at a Single Academic Hospital Study design and selection of patients We conducted a retrospective cross-sectional study that included adult patients (18 years or older) who underwent craniotomy for brain tumour resection at a single academic medical centre in Los Angeles, California from March 2013 to January 2017. Patients were selected using International Classification of Diseases, 9th and 10th Revision and Current Procedural Terminology, version 4 codes. Informed consent was obtained from all individual participants included in the study. The study had prior approval from our institutional review... 
Applied Microbiology: Open Access- Invitation on Special Issues Applied Microbiology: Open Access is a scholarly open access journal that deals with the study of Medical microbiology the study of the pathogenic microbes and the role of microbes in human illness, Pharmaceutical microbiology the study of microorganisms that are related to the production of antibiotics, enzymes, vitamins and vaccines, Industrial microbiology the exploitation of microbes for use in industrial processes It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue in the... 
Applied Microbiology: Google scholars Applied Microbiology is a peer-reviewed Open Access Journal, encourages on-going international research and articles related to but not limited to Medical microbiology, pathogenic microbes, Pharmaceutical microbiology (antibiotics, enzymes, vitamins, vaccines) Industrial microbiology, Microbial biotechnology, Plant pathology, Veterinary, Food, Agricultural, Soil, Environmental Microbiology, etc. It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue in the form of Research, Reviews, Commentaries, Letter to Editor, Case Reports, Short Communication, Images, Conference Proceedings which will be published in our journal.... 
The 
We propose a new 
Our aim is to provide the surgeons, refractive surgeons, optometrists, opticians, young researchers, students, industrial delegates and anyone professionally involved in study of 
International journal of 
On behalf of the 
Natural Products Chemistry and research is a peer-reviewed Journal, encourages on-going international research and information exchange through publication of latest advances. The Journal is pleased to inform that it is been running successfully since 7 years and is running towards its 8th Anniversary. It is an Open access scholarly Chemistry and Natural Medicine journal with an ISSN No: 2329-6836. This journal is known for its quality research articles in the field of Agricultural Chemistry, Pharmacognosy, Alkaloids, Flavonoids, Bioactive compounds, Biochemistry, Physical Chemistry, Phytochemistry, Natural Medicine, Herbal Medicine, Phytomedicine, Marine drugs, Natural products and Horticulture. The journal is indexed in... 
In recent years, technological advancements in transcriptomics (the process of studying a cell’s complete set of 
Metastatic neuroblastoma with opsoclonus raccoon eye presentation is an extremely rare condition presented in stage IV metastatic condition. Histopathology/ cytology, vanillylmandelic acid (VMA), homovanillic acid (HVA) levels and metaiodobenzylguanidine (MIBG) scanning are mainly contributors for the diagnosis of this disease. We are presenting one year male child with history of protrusion of right eye, swelling in right periauricular region, opsoclonus movements of small amplitude and periorbital ecchymosis ‘raccoon eye’. So far only infinitesimal cases has been reported in the literature and our present case report is an extremely rare case of locally advanced metastatic neuroblastoma, who presented as opsoclonus raccoon... 
In recent years, healthcare data analysis is becoming one of the most promising research areas. Healthcare includes data in various types such as clinical data, Omics data, and Sensor data. Clinical data includes electronic health records which store patient records collected during ongoing treatment. Omics data is one of the high dimensional data comprising genome, transcriptome and proteome data types. Sensor data is collected from various wearable and wireless sensor devices. To handle this raw data manually is very difficult. For analysis of data, machine learning is emerged as a significant tool. Machine learning uses various statistical techniques and advanced... 
Mechanism of Low Endotoxin Recovery Caused by a Solution Containing a Chelating Agent and a Detergent Mechanism of Low Endotoxin Recovery (LER) was investigated by observing the change in particle sizes and activity of endotoxin in LER solutions containing sodium citrate and polysorbate 20. Interestingly, endotoxin aggregates were not dispersed to be smaller particles under LER conditions according to the decease of the activity. This observation was different from previous predictions of the mechanism. Endotoxin aggregates were observed by Dynamic Light Scattering, and activity was measured by the Limulus amebocyte lysate test. Particles with sizes similar to endotoxin aggregates were... 
Journal of Vaccines & Vaccination is on the leading open-access journal making awareness to the people on vaccination through our articles. We have been 
Accumulating evidence shows that tumours contain a distinct subpopulation of cancer stem cells (CSCs) which are capable of self-renewal, differentiation, and tumour-initiation. Previous studies have demonstrated that cancer stem cells are relatively resistant to chemo-and radio-therapies, and play an essential role in tumour recurrence and metastasis. Since multiple human malignancies are associated with quantitative and qualitative deficiencies in the immune system, immunotherapies are potentially ejective for cancer treatment. Vaccination is believed to have advantages over traditional treatments due to its potential to possibly eradicate the micrometastases that tend to linger after standard treatments. However, to date, experimental evidence remains limited... 
Chronic Abdominal Pain following the TAPP Hernioplasty, Caused by Appendix Attached to the Polypropylene Mesh We report a case of 42 y old male patient with chronic pain in the lower right abdominal quadrant that appeared almost every time after or during exercise, for a last two years. The patient underwent transabdominal preperitoneal patch hernioplasty (TAPP), due to the right inguinal hernia two and a half years ago. There were no comorbidities or other previous operations in his medical records. Since the abdominal ultrasound (US) and magnetic resonant (MR) with laboratory methods did not show any special findings, the laparoscopy... 
Special Issue Guidelines for Hair Therapy and Transplantation Longdom Publishing SL welcomes proposals for special issue that falls within the scope of the Hair Therapy and Transplantation Journal. The special issue aims at exploring new, relevant, and the most compelling dimensions in the field of Hair Therapy and Transplantation that missed a mention in the journal on a regular basis. Proposal Preparation Special issues will be released on a monthly basis and proposals will be accepted accordingly. All proposals should include the following information: Title of the proposed special issue Purpose and current relevance List of topics to be... 
The Journal is successfully running in the 4th Volume which covers a wide variety of specialties including 
Journal of Plant Biochemistry & Physiology is celebrating 7th Anniversary it’s been seven years we have started the Journal. The open access journal is published by Longdom who hosts around 350 open access peer-reviewed journals as well as organizes more than 100 International scientific Conferences. We are privileged to welcome 
Journal of Thyroid Disorders and Therapy Announces Reasonable Discounts Journal of Thyroid Disorders and Therapy has announced almost 50 percent discount on article processing charge to commemorate its Anniversary. 
Commentary This paper is based on a scenario of a 30-year old young man with end-stage lymphoma. Нe mother wanted to do all possible interventions to treat his son. Нe medical team concluded that there is no further treatment option available. Нe physician wanted to send the patient home to spend time with his family and to prevent hospital induced complications, whereas the mother was not willing to take him home. In such situation, what would be the possible best decision for the patient who has a short expected survival time? Нe analysis of the above case study highlighted... 
Forensic pathology is a specific branch of medicine that focuses on determining the cause of death by examining a corpse. A post mortem is performed by a medical examiner, usually during the investigation of criminal law cases and civil law cases in some jurisdictions, the principles and knowledge of medicine and related sciences to problems that concern the general public and related legal issues. A forensic pathologist is a physician with specialized medical and forensic science training and knowledge. In practice, forensic pathologists concentrate closely on the understanding of types and causation of injuries and causes of sudden and unnatural death. The roles of the forensic pathologists includes examination of the death... 
Journal of Cancer Research and Immuno- Oncology is an international, peer-reviewed journal which publishes high quality manuscripts from basic, fundamental, applied research developments in cancer research and its immunology. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. The main aspects of research areas include, but are not exclusive to cancer biology, tumor, radiology, metastatis, cancer immunotherapy, oncology, radiation therapy etc., 
Natural Products Chemistry and Research is an open access Scientific Journal which mainly focuses on articles of Chemistry. The Journal of Natural Products Chemistry and Research comes up with an opportunity to researchers and scientist to explore advance research in Chemistry. The Natural Products Chemistry and Research is of highest standards in terms of quality. The editorial team of Natural Products Chemistry and Research is overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal. During this year we look forward to taking some initiates that would encourage and reward our... 
Journal of Developing Drugs is a peer-reviewed Journal, encourages on-going international research and information exchange through publication of latest advances. The Journal is pleased to inform that it is been running successfully since 8 years and is running towards its 9th Anniversary. It is an Open access scholarly Developing Drugs journal with an ISSN No: 2329-6631. This journal is known for its quality research articles in the field of Pharmaceutics, Nanotechnology, Novel Drug Delivery Systems, Quality Control, Quality Assurance, International Regulatory, Validation Techniques, Industrial Pharmacy, BioTechnology, Bioinformatics, Proteomics, Biochemistry, Pharmacognosy, Pharmaceutical Analysis, PK/PD, Drug Development, Pharmacology and Toxicology, Pharmacy... 
The team “
Introduction I would like to commence my commentary article with the most frequently asked question in every society that why does man become a drug addict? Нe answer is that, one usually does not intend to become an addict. Someone woke up in the morning and become a drug addict, studies has shown that it takes at least three months’ shooting twice a day to get any habit. Studies have proven that mostly drugs addict’s start taking narcotics without any reason (WHO, 2011).
Information fusion The 
Our aim is to provide the surgeons, refractive surgeons, optometrists, opticians, young researchers, students, industrial delegates and anyone professionally involved in study of 
Google Analytics of Applied Microbiology: Open Access 
Applied Microbiology: Open Access-Reviewer Invitation Applied Microbiology is a peer-reviewed Open Access Journal, encourages on-going international research and articles related to but not limited to Medical microbiology, pathogenic microbes, Pharmaceutical microbiology (antibiotics, enzymes, vitamins, vaccines) Industrial microbiology, Microbial biotechnology, Plant pathology, Veterinary, Food, Agricultural, Soil, Environmental Microbiology, etc. 
Journal of Vaccines & Vaccination has completed 8 years of successful journey, now we are in 9th year for continuing the excellence in the publication field with the help of our glorious editors. We are 
Journal of 
Co The perspective of the 
New Issue Release 2020 -Journal of genetics syndrome and gene therapy[Upcoming Issue] The 
Genetic syndromes Journal of 
.... 
The Recent published article in the 
First Published Article: Journal of Astrobiology & Outreach The very first published article in the 
Primary Mixed Adenoneuroendocrine Carcinoma (MANEC) of Gallbladder Mixed adenoneuroendocrine carcinoma (MANEC), described and recognized by WHO in 2010, is a rare gastrointestinal neoplasm [1], characterized by the presence of at least 30% each of epithelial and neuroendocrine components [2]. Нe tumor may appear in various levels of the digestive tract including the oesophagus, stomach, colon and appendix, as well as other sites, such as the bladder. MANEC is an exceptionally rare neoplasm of gallbladder. Нe neoplasm occurs mostly in the middle-aged to elderly females with mean age of 64 years. Based on few case studies, suggested pathogenesis includes intestinal... 
Journal of Tumor Research: Chemotherapy for Stage II Classical Hodgkin Lymphoma Journal of Tumor Research is an open access journal which covers different areas of all the tumors and cancer including breast cancer, prostrate, Lung cancer, ovarian cancer, malignant tumor cells, brain tissue, neurofibromatosis, multiple endocrine neoplasia, meningioma, neuroblastoma, astrocytoma and brain neoplasm. The most common type of tumors are glioblastoma and glioma. A metastatic tumours are the cancer cells that develop in a body organ such as the lung can spread via direct extension, or through the bloodstream to other body organs such as the brain. Other types of... 
Manuscript Submissions: Journal of Thyroid Disorders and Therapy 
Manuscript Submissions: Hair Therapy and Transplantation 
SYPHILIS Syphilis is a highly contagious disease that’s mostly spread through sexual activity, including oral and anal sex. The infected person often doesn’t know that they have the disease and passes it on to their sexual partner. Syphilis was once a major public health threat. It can cause serious long-term problems such as arthritis, brain damage, and blindness. There wasn’t an effective treatment until the late 1940s, when the antibiotic penicillin was developed. After the initial infection, the syphilis bacteria can remain inactive (dormant) in your body for decades before becoming active again. Early syphilis can be cured, sometimes... 
Peritoneal Carcinomatosis in Well-Differentiated Small-Intestinal Neuroendocrine Tumors with Mesenteric Tumor Deposits Objective: Well-differentiated small-intestinal neuroendocrine tumors (SI-NETs) tend to be biologically indolent.Despite this tendency, they have a predilection for metastasis. Peritoneal involvement is quite common as isunfortunately peritoneal carcinomatosis (PC). PC is a dreaded metastatic complication due to the significant morbidity it creates for patients as well as well as increasing their mortality risk. The risk factors for PC development in SI-NETs remain understudied; however, one such factor may be the presence of mesenteric tumor deposits (MTDs). Methods: We performed a retrospective analysis on 208 well-differentiated SI-NET patient samples, the... 
Guillain-Barre syndrome (GBS) is an acute demyelinating inflammatory mediated polyneuropathy mediated by the immune system that leads to generalized flaccid paralysis. Most GBS cases are preceded by viral or bacterial infections of the respiratory or gastrointestinal tract, developing an aberrant response that causes autoantibody formation and complement and cytokine activation. Because it is a rare disease, diagnosis is often slow and may worsen the clinical picture. The patient should be evaluated by a multidisciplinary team and the treatment of choice is intravenous human immunoglobulin. We report a case in which the patient had several symptoms resulting from GBS, probably developed... 
Kidney Infection Diagnosis Kidney infection, also known as renal infection or pyelonephritis, is a common type of urinary tract infection. Bacteria often infect the bladder or the urethra and spreads to one of the kidneys. Women are most commonly affected by kidney infection, as are pregnant mothers, children under 2 years of age, and individuals aged over 60 years. This article will explain the symptoms of a kidney infection and how it is diagnosed, prevented, and treated. Some key points about kidney infections: One of the kidney's major roles is to remove toxins from the body. Symptoms of... 
Who are we? The “
Excessive bleeding often complicates spine surgery. This may result in increased morbidity and mortality. The amount of blood loss depends on many factors. Нe extent of a surgical procedure is the principal cause of a blood loss during spine surgery. Perioperative coagulation dysfunction is also an important factor leading to an excessive blood loss during lengthy spinal surgeries. Tranexamic Acid (TA) is safely used for the prevention of blood transfusion for major joint replacement procedures. The benefit and safety of tranexamic TA in patients undergoing major spinal fusion is not completely established. Nevertheless, TA appears to have a potential role... 
Instructions for authors for submissions: Hair Therapy and Transplantation 
Instructions for authors for submissions: Journal of Thyroid Disorders and Therapy 
Journal of Surgery and Anesthesia is a peer reviewed, open access journal dedicated to publishing research on all aspects of surgery and anaesthesia. This journal aims to keep anaesthesiologists, anaesthetic practitioners, surgeons and surgical researchers up to date by publishing clinical & evidence based research. Journal of Surgery and Anesthesia addresses all aspects of surgery & anesthesia practice, including anesthetic administration, pharmacokinetics, preoperative and postoperative considerations, coexisting disease and other complicating factors, General Surgery, Robotic Surgery, Orthopedic Surgery, GI Surgery, Neurosurgery, Plastic Surgery, Cardiothoracic Surgery, Vascular Surgery, Urology, Surgical Oncology, Radiology, Ophthalmology, Pediatric Surgery, Trauma Services, Minimal Access Surgery, Endocrine... 
Journal of Next Generation Sequencing & its Applications- NGSA (ISSN:2469-9853) aims to serve as a platform to young buddies in emerging and developing research areas in chemical sciences like DNA Sequencing, G protein–coupled receptor, mitosis-promoting factor, RNA processing, Whole genome sequencing, complementary DNA, Western blotting, microtubule-associated protein, allosteric transition, zinc finger, autonomously replicating sequence and to link with centers of excellence worldwide to provide authoritative coverage and references in focused and specialist fields. The Journal of Next Generation Sequencing & its Applications aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all... 
Journal of Developing Drugs is an open access Scientific Journal which mainly focuses on articles of Drug designing. The 
On behalf of the Journal, as Editor-in-Chief, it is my distinct honour and privilege to welcome you to the Journal of Theoretical and Computational Science. The 
On the occasion of entering into its 5th anniversary Immunotherapy: Open access wants to thank the most cited research in the journal. The article entitled “Joint Action of the Nano-sized System of Small Non-coding RNAs with DDMCVector and Recombinant IL-7 Reprograms A-549 Lung Adenocarcinoma Cellsinto CD4+ Cells” by the researcher Oxana V. Klimenko from SID ALEX GROUP, Ltd. Kyselova 1185/2, Prague, Czech Republic. The abstract of the article is as follows: Small non-coding RNAs, as class of small regulatory molecules, control normal development and differentiation ofcells. ... 
Journal of Astrobiology & Outreach-A view of Special Issue Astrobiology is the study of life in the universe. The search for life beyond the Earth requires an understanding of life, and the nature of the environments that support it, as well as planetary, planetary system and stellar processes. To provide this understanding, astrobiology combines the knowledge and techniques from many fields, including astronomy, biology, chemistry, geology, atmospheric science, oceanography and aeronautical engineering. Journal of Astrobiology & Outreach seeks innovative proposals to create special issues related to research works in environmental and allied sciences. Through special issues addressed to specific challenges... 
Current research on Genetic Syndrome and Gene Therapy The Journal of 
Use of genomics to balance cure and complications The Journal of 
Journal of Tumor Research: Manuscipt submission. Journal of Tumor Research - Open Access using online manuscript submission, review and tracking systems of Longdom Publishing SL for quality and quick review processing. Longdom Publishing SL is using Online Review and Editorial Tracking Systems for quality review process. Editorial Managerial System is an online submission and review system, where authors can submit manuscripts and track their progress. Reviewers can download manuscripts and submit their opinions. Editors can manage the whole submission/review/revise/publish process. Publishers can see what manuscripts are in the pipeline awaiting publication. E-mail is sent automatically to concerned persons when significant... 
The injuries of major airways in high speed motor vehicle accidents is a relatively uncommon with a reported incidence of 0.03%-3%.Besides blunt chest injuries, the presence of associated other multiple injuries (head, facial, spine, abdomen, vascular and orthopaedic) are important determinants of outcome. In 25% of cases, deaths are due to thoracic trauma. The airway injury is mostly fatal and it is reported that a large proportion (81%) of the airway injury patients died immediately or before reaching the hospital due to tension pneumothorax. The incidence of trachea-bronchial tree injury is0.5% in blunt trauma and 1-2% in penetrating trauma. Isolated... 
Journal of Tumor Research: Special Issue Special Issue Guidelines (Clinical) Longdom Publishing SL welcomes proposals for creating special issues that fall within the scope of the Journal of Tumor Research published by Longdom Publishing SL. The special issue aims at exploring new, relevant, and most compelling dimensions in the field of Tumor Research and its therapy that missed a mention in the journal on a regular basis. Proposal Preparation Special issues will be released on a monthly basis and proposals will be accepted accordingly. All proposals should include the following information: Title of the proposed special issue Purpose and current... 
Applied Microbiology: Open Access –Invite to Reviewers 
Applied Microbiology: Open Access-an overview Applied Microbiology is a peer-reviewed Open Access Journal, encourages on-going international research and articles related to but not limited to Medical microbiology, pathogenic microbes, Pharmaceutical microbiology (antibiotics, enzymes, vitamins, vaccines) Industrial microbiology, Microbial biotechnology, Plant pathology, Veterinary, Food, Agricultural, Soil, Environmental Microbiology, etc. Applied Microbiology: Open Access follows Editorial Tracking System for quality in peer review process. Editorial Tracking is an online manuscript submission, review and tracking systems used by most of the best open access journals. The 
The team “
Machine Learning and Computational Intelligence There is an increasing need for the application of 
"
Acanthamoeba Keratitis 
Scope of Drug Designing: Open Access Journal 
Statistical Designs for Pharmaceutical 
Introduction The case: In 2004 in a Saudi public hospital, an 18-year-old single, Muslim female presented with 15 weeks pregnancy. She was accompanied with her mother who approached the family physician asking for abortion because both the mother and the daughter were afraid from her family’ reaction. The case in global and local contexts: Abortion, in general, and particularly what could be referred to as ‘socially-induced’ abortion is not uncommon in many parts of the world. In 2011, an estimated 1.1 million abortions were performed in the United States; the abortion rate was 16.9 per 1,000 women aged 15-44,... 
Most Cited editorial was published in Transcriptomics: Open Access Journal was by editor Alireza Heidari in 2017 entitled “
On behalf of the 
Inviting you to Join as an Editorial Board for Hair Therapy and Transplantation: Open Access Journal Hair Therapy and Transplantation is one of the best open access journal that aims to publish the most complete and reliable source of information on discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in the field and provide free access through online without any restrictions or any other subscriptions to researchers worldwide. This top best scholarly journal is using Editorial Tracking System for quality in online manuscript submission, review and tracking system. Editorial board members... 
On behalf of the 
Risk Factors for Febrile Seizures in Children Objective: we aimed to identify the factors associated with febrile seizures (FS) occurrence. Methods: This was a case-control study. Sixty cases of FS were prospectively recorded and compared to 60 controls admitted for fever without seizures. Baseline Data were collected from all consecutive patients and laboratory hematological parameters including complete blood count, serum iron, serum ferritin and zinc levels were performed prospectively the first day of admission. The two groups were compared to identify parameters associated with FS occurrence. All statistical analysis was performed with SPSS software, version 19. Results: The mean age was 18... 
The Presence of Autonomous and Non-Autonomous Replication in Cancer and their Connection through Inflammation Targeted therapy with small molecule such as TKI (tyrosine kinase inhibitor) against EGFR has achieved high response rate and significant clinical benefits in selected group of lung cancer patients in the past decade. One reliable criterion for patient selection is the presence of certain mutations in the EGFR gene such as mutations in exon-19, 20 or 21 in lung cancer patients. In these patients, it is often observed that TKI therapy could be so effective even against late stage tumors, that patients experience rapid relieve of... 
Join the Community of Hair Therapy and Transplantation to Vast and Diverse Research. 
Immunotherapy: Open Access is a peer reviewed journal emphasizes the scientific research and education with in the field of immunotherapy. Journal has opened submissions for its upcoming issue and volume which is volume 5 Issue 1. On the occasion of its 5th anniversary journal is providing the discount on the article processing charges for those who are submitting for upcoming issue. As the Journal is open access there are more benefits for publishing along with us. Through Open Access publication, authors benefit in number of ways: Standards of high-quality, rapid peer-review and production Enhances the visibility... 
On behalf of the Journal, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Theoretical and Computational Science. The 
Social science is the field of sciences concerned with the studies of the social life of human groups and individuals. Social studies is a term used to describe the broad study of various fields which involves past and current human behavior and interactions. Research &Review: Journal of Social Science on discovery and innovation in various aspects like Sociology, Geography, Economics, History, Cultural studies, Ethnography, Sociolinguistics, Home science, Demography, Political sciences etc Reviews, Mini Reviews, Short Communications, Perspectives/Opinions, Letters, Short Note and Commentaries are accepted for publication. This is an open access journal where one can find scientific research as in... 