Recent Advances in HBV and HCV Immunology

Image More than 500 million people worldwide are persistently infected with the hepatitis B virus (HBV) and/or hepatitis C virus (HCV). Persistently infected individuals can develop chronic liver disease, cirrhosis and hepatocellular carcinoma. HBV and HCV share numerous pathogenic mechanisms and strategies of immune escape. Cytotoxic, helper, and regulatory T cells, dendritic cells (DCs), natural killer (NK), iNKT, and B cells play important roles in HBV and HCV clearance. T cell responses are crucial to prevent and control viral infection; however, virus-specific T cell activities may... Read More

Advancement in Immunology system and Cancer

Image The Research Topic is designed to feature the latest innovative and leading-edge research, reviews and opinions on the study of complex and dynamic processes related to the mammalian immune system and cancer. All papers will be meticulously selected to present our readers the multidisciplinary approach to tackle the existing challenges faced in these important fields. From high throughput experimental methodologies to computational and theoretical approaches, the articles are intended to introduce physicists, chemists, computer scientists, biologists and immunologists the idea of ... Read More

Gene Expression - Translation

Image Gene Expression - Translation Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do?. Moreover, each step in the flow of information from DNA to RNA to protein provides the cell with a potential control point for self-regulating its functions by adjusting the amount and type of proteins it manufactures. At any given time, the amount of a particular protein in a cell reflects the balance between that protein's synthetic and degradative biochemical pathways. On t... Read More

Genomics Brings Heavy Lifting to Immuno-Oncology: A Special Issue

Image Cancer is one of the most vicious disease which is devastating many lives psychologically, physically and in an unhealthy manner. The treatment of cancerous diseases is becoming a major challenge for the scientists and researchers working on chemotherapeutic agents. Traditional pillars of cancer treatment – Surgery, Radiation, and Chemotherapy are moving to two new efficacious approaches: Cancer genomics and immunotherapy. Cancer genomics is the study of the totality of DNA sequence and gene expression differences between tumour cells and norm... Read More

HLA Allele Distribution in Romanian People: Clinical Significance and Utility Related to Population Genetic Background

Image HLA Allele Distribution in Romanian People: Clinical Significance and Utility Related to Population Genetic Background He HLA complex is defined by the genes of the Major Histocompatibility Complex (MHC). Нese loci play a key role in the immune system response and are among the most polymorphic in humans, comprising more than 20 genes, Here loci have been studied extensively for at least four reasons: (i) for donor-recipient matching in organ and stem cell transplantation success, (ii) due to associations between polymorphisms and response to infectious diseases ... Read More

MHC Genotyping from Rhesus Macaque Exome Sequences

Image MHC Genotyping from Rhesus Macaque Exome Sequences Immunogenetics: Open Access has been recently launched an article entitled “MHC Genotyping from Rhesus Macaque Exome Sequences”. It is the most cited article published in the Volume 4 in 2019. Here we are explaining introduction and conclusion of an article. The major histocompatibility complex (MHC) is an intensively studied set of genes in macaques [1,2]. The genomic MHC region contains clusters of genes ... Read More

Diagnostic Biomarkers

Image Diagnostic Biomarkers Diagnostic biomarkers are used to confirm that a patient has a particular health disorder. For example, the presence of mutations in the CFTR gene indicate that a newborn has cystic fibrosis. It is “a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.” An biomarker has certain characteristics that make it useful for checking on one’s health or disease conditions. An ideal marker should be:... Read More

New gene correction therapy for Duchenne muscular dystrophy

Image Author Name: Keith Howell Category: Genetics and molecular Biology Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of twelve and reducing life expectancy. Researchers at Technical University of Munich (TUM), Ludwig Maximilian University of Munich (LMU) and the German Research Center for Environmental Health (Helmholtz Zentrum München) have developed a gene therapy that may provide permanent relief for those suffering from DMD. ... Read More

Genome stability in DNA

Image It gives us great pleasure to announce the call for paper on the occasion of 05th Anniversary of the Journal .The Journal of Cell Signaling accepts all types of articles including research, review, case reports, commentaries, hypotheses, meeting reports and short reports. This scientific journal is using Editorial Tracking System for maintaining quality in peer review process. Author Name: Keith Howell Category Name: Genetics an molecula... Read More

MYC Transcriptomics

Image MYC is a transcriptional factor and a proto-oncogene that is frequently deregulated in a wide array of cancers. Myc family genes include MYC, MYCN and MYCL1, which encode nuclear phospho proteins and function as sequence specific transcription factors that regulate large number of genes. All the MYC family members have been implicated in a wide variety of human hematological malignancies and solid tumors. Of all the Myc family proteins, the MYC transcription factor is extensively studied... Read More

Extracellular Vesicles and Their Role in Immunomodulation and Cancer

Image Extracellular vesicles (EVs) including exosomes, microvesicles, and apoptotic bodies are membrane-bound vesicles which are secreted by almost all cell types to the cellular microenvironments and circulation. EVs contain bioactive cargoes such as antigens, cytokines, chemokines, membrane proteins, lipids, microRNAs, and long non-coding RNAs that have the ability to elicit cellular responses. EVs can be released by and also be targeted toward immune cells and act as key mediators of cellular communications. EVs carry specific molecular signatures reflecting the status of parental cells at the... Read More

Frameworks for Interpreting Cancer Progression and Immune Response for Drug Discovery and Development

Image The development of technologies to better characterize patient disease states, including methods such as sequencing, microarrays, metabolomics, and proteomics from multiple tissues, has produced datasets with potential utility in discovering new targets and identification of patients who might benefit from a given therapy. However, establishing a context for the high dimension content of omics datasets is necessary in order to maximize their predictive potential for the impact of single or combination therapies. Progress towards frameworks for omics data interpretation has arguably been une... Read More

Genetic disorders

Image Genetic disorders Journal of Genetic Syndromes & Gene Therapy is an open access publisher which provides scientific information to all the researchers and academicians in all quarters. Journal of Genetic Syndromes & Gene Therapy (JGSGT) brings articles in all areas related to Genetics such as Genetic disorders, Genetic mutations, Auto immune diseases etc on Quaterly basis. JGSGT welcomes the submission... Read More

Chromosome abnormality

Image A chromosomal disorder, anomaly, aberration, or mutation is a missing, extra, or irregular portion of chromosomal DNA.It can be from a typical number of chromosomes or a structural abnormality in one or more chromosomes. Chromosome mutation was formerly used in a strict sense to mean a change in a chromosomal segment, involving more than one gene. The term "karyotype" refers to the full set of chromosomes from an individual; this can be compared to a "normal" karyotyp... Read More

Novel Strategies for Cancer Immunotherapy: Targeting Immune-Mediated Suppressive Mechanisms

Image Over the past decade, novel forms of cancer therapies, collectively referred to as cancer immunotherapies, have emerged and yielded spectacular results in unfortunately still a minority of cancer patients. Immunotherapies mobilize the immune system to promote or restore effective anti-tumor immune responses. Pioneer approaches targeting the CTLA-4/B7 and PD1/PDL1 immune checkpoint axes have now reached broad clinical applications. Such treatments often yield sustained benefits, but strong responses are observed in only a minority of treated patients, whereas resistance to immune checkpoint ... Read More

Dendritic Cell-based Immunotherapy in Solid and Haematologic Tumors

Image Dendritic cells (DCs) play a critical role in orchestrating antitumor immune responses due to their capability of regulating innate and adaptive immunity. DCs can elicit tumor specific cytotoxic immunity through both the induction of antigen-specific CD4+ and CD8+ T lymphocytes and the stimulation of killing activity of innate immune cells, such as NK cells and NKT cells. Although a compelling body of preclinical studies strongly supports the potential application of DCs in the treatment of solid and hematologic tumors, DC-based immunotherapy remains rarely used in the clinical practice. Mo... Read More

Neoantigens Generated by Individual Mutations and Their Role in Immunity and Immunotherapy

Image This “Research Topic” is a call for papers to provide an up-to-date overview of current efforts to understand the immunological mechanisms of neoantigen directed T-cell immunity and the attempts to harvest this source of antigens for cancer immunotherapy. Recently, the work of different groups revealed that neoepitope-specific T cells are crucial for clinical responses mediated by adoptive transfer of autologous TILs or by immune checkpoint inhibitors. Moreover, ongoing clinical trials demonstrated clear evidence for the feasibility of individualized vaccination or adoptive cell... Read More

Issues and Challenges in NSCLC Immunotherapy

Image Immunotherapy is a modern and extremely promising treatment for non-small cell lung cancer (NSCLC) patients, often providing long-term clinical benefits or even, in some cases, a complete recovery. Although many patients can now benefit from this form of treatment, the major limitations include high variability in response to treatment and difficulties in the proper qualifications for therapy. Precise predictive factors for immunotherapy have not been determined yet, and this remains subject to further research. Examination of PD-L1 expression on cancer cells and tumor mutati... Read More

Evidence-based Advance and Management of Adverse Events of Immunotherapy for Cancer

Image Immunotherapy, which activates the body’s immune system, has drawn great attention in recent years due to its significant effects. It has been more than 100 years since the first immunotherapy report in 1911 by Leonard Noon. In 1954, Frankland reported the first double-blind placebo-controlled randomized trial in immunotherapy. Since then, immunotherapy has been utilised in different diseases, including asthma and reactions to skin allergens.   Harnessing the immune system for therapeutic benefit in cancer has long been an aim of immunologists and oncologists.... Read More

New technology allows control of gene therapy doses

Image The feat, reported in the scientific journal Nature Biotechnology, offers gene therapy designers what may be the first viable technique for adjusting the activity levels of their therapeutic genes. The lack of such a basic safety feature has helped limit the development of gene therapy, which otherwise holds promise for addressing genetically based conditions. The scientists' technique appears to solve a major safety issue and may lead to more use of the strategy. ... Read More

Researchers uncover the genomics of health

Image A baseline of healthy ageing Every person has around 6 billion DNA 'letters' in their genome, which encodes all of the information needed to make and run every cell in the body. Between any two unrelated people, there are millions of single letter differences, or variations. Variations make us different, but some of them can cause disease—the challenge for researchers is to pinpoint which these are. The authors of the current p... Read More

Jumping genes also provide genomic stability

Image The DNA molecule inside the nucleus of any human cell is more than six feet long. To fit into such a small space, it must fold into precise loops that also govern how genes are turned on or off. It might seem counterintuitive that bits of DNA that randomly move about the genome can provide stability to these folding patterns. Indeed, the discovery contradicts a long-held assumption that the precise order of letters in the DNA sequence always dictates the broader structure of the DNA molecule. In places where the larger 3D folding of the genome is the same between mice and humans, ... Read More

Genetic Syndrome and Gene Therapy New Arena

Image Genetic Syndrome and Gene Therapy New Arena Visakhapatnam, 29-11-2019 The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to genetics. On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the J... Read More

Gene Expression New arena

Image Gene Expression New arena Visakhapatnam, 29-11-2019 Journal of Genetic Syndromes & Gene Therapy enhancing the academic communication between scholars and seeking professionals to join as an editorial board Member (or) reviewer team. The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on... Read More

Identification of Novel MicroRNAs and their Target Prediction in Stevia rebaudiana

Image miRNAs are a class of endogenous, small, noncoding, ~22 nucleotides single-stranded RNAs that act as posttranscriptional regulators in eukaryotes . They have reported to be located mostly within noncoding regions of genomes, and usually transcribed from RNA polymerase II promoters . The generation of mature miRNA is a complicated enzyme-catalyzed process, from the initial transcript pri-miRNA to the precursor (pre-miRNA) with a characteristic hairpin structure, then a miRNA duplex (miRNA:miR... Read More

A breakthrough for a rare genetic disorder

Image Duchenne Muscular Dystrophy (DMD) is a rare genetic disorder that has affected 0.8 million male children in India. DMD occurs due to deficiency in the manufacture of dystrophin — a protein located primarily in skeletal muscles — used during movement, besides in other organs such as lung, heart and in the brain’s nerve cells. This affects their functioning. The symptoms include muscle degeneration and weakness, which goes on to affect various physiological acti... Read More

Cell Structure of Human cell recently discovered

Image Author Name: Keith Howell Category Name: Genetics and molecular Biology Description: Cell Structure of Human cell recently discovered  The structure is a new type of protein complex that the cell uses to attach to its surroundings and proves to play a key part in cell division.The cells in a tissue are surrounded by a net-like structure called the extracellular matrix. To attach itself to the matrix the cells have receptor molecules on their surfaces, which control the assembly of large protein complexes i... Read More

Types of Immunotherapies

Image Immunotherapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as activation immunotherapies, while immunotherapies that reduce or suppress are classified as suppression immunotherapies.   In recent years, immunotherapy has become of great interest to researchers, clinicians and pharmaceutical companies, particularly in its promise to treat various forms of cancer.   Immunomodulators:  Immunomodulators are the acti... Read More

Immuno-Oncology | Cancer research

Image Cancer immunotherapy (sometimes called immuno-oncology) is the artificial stimulation of the immune system to treat cancer, improving on the immune system's natural ability to fight the disease. It is an application of the fundamental research of cancer immunology and a growing subspeciality of oncology. It exploits the fact that cancer cells often have tumor antigens, molecules on their surface that can be detected by the antibody proteins of the immune system, binding to them. The tumor antigens are often proteins or other macromolecules (e.g. carbohydrates). Normal antibodies bind to... Read More

Proteomics Is Ready for Primetime

Image Over the past two decades, medicine has been moving towards data-driven diagnoses and personalized therapies based on molecular information.1 Oncology is a prime example, with an ever-growing range of precision drugs designed to target specific driver mutations in cancer cells. However, while these drugs have provided some benefits, they have failed to transform survival in most tumor types. Frustratingly, identification of a particular genetic alteration is not enough to guarantee that a treatment will work. For example, drugs targeting the overactive V600E f... Read More

Diagnosing rare diseases using RNA: A Q&A

Image Every person distills down to a script of DNA, and researchers are increasingly mining this genetic information to better inform care. Now, scientists have shown how RNA -- an offshoot of DNA -- is coming into its own as doctors sleuth out difficult-to-diagnose illnesses. In a new study in Nature Medicine, Stephen Montgomery, PhD, a Stanford associate professor of pathology and of genetics, shows why the transcriptome, the collection of RNA molecules in a cell, is a crucial clue to help decipher the source of some rare diseases. I had a chanc... Read More

Gene Mutations

Image Gene Mutations   Mutations are changes in the genetic sequence, and they are a main cause of diversity among organisms. These changes occur at many different levels, and they can have widely differing consequences. In biological systems that are capable of reproduction, we must first focus on whether they are heritable; specifically, some mutations affect only the individual that carries them, while others affect all of the carrier organi... Read More

Journal of Genetic Syndromes & Gene Therapy

Image Journal of Genetic Syndromes & Gene Therapy Journal of Genetic Syndromes & Gene Therapy is an open access publisher which provides scientific information to all the researchers and academicians in all quarters. This Genetics journal is using Editorial Manager System for online manuscript submission, review and tracking. Editorial board members of the Genetic Syndromes & Gene Therapy or outside experts review... Read More

MicroRNAs in the Cholinergic Anti-Inflammatory Pathway: Immunotherapy

Image Immunotherapy: Open Access was congratulating its authors of most cited articles. The article entitled “MicroRNAs in the Cholinergic Anti-Inflammatory Pathway: ProspectiveTherapeutic Targets for Inflammatory Diseases” which was written by Yang Sun and Xia Liu was mostly cited article which was published in 2016 from Department of Pharma... Read More

Cancer research and Immuno-Oncology

Image Cancer immunotherapy is a therapy used to treat cancer patients that involves or uses components of the immune system. Some cancer immunotherapies consist of antibodies that bind to, and inhibit the function of, proteins expressed by cancer cells. Other cancer immunotherapies include vaccines and T cell infusions.   Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone thera... Read More

Comparative and Evolutionary Studies of the Lysosomal 2-Sulfoglucuronate Sulfatase

Image Arylsulfatase K (ARSK) is one of 17 sulfatase gene family members encoded on the human genome for which a role has been recently identified as a lysosomal 2-sulfoglucuronate sulfatase. Vertebrate ARSK sequences shared 60-82%identity but only <27% identities with other arylsulfatase family members. Comparative enzyme structures were studied,including residues wi... Read More

Current trends in Cancer Research and Immuno-Oncology

Image Journal of Cancer Research and Immuno-Oncology is one of the most promising and rapidly developing areas of cancer research. The journal focuses on the development of new therapies which improve human body’s immune response against cancer.Journal of Cancer Research and Immuno-Oncology covers a broad scope for the authors to make their valuable contributions in the area of cancer biology, tumor and stem cell biology, immunology, microenvironment and immunology, molecular and cellular pathobiology, immuno-oncology, prevention and epidemiology, therapeutics and targets.  ... Read More

A new RNA sequencing approach: what is single cell transcriptomics?

Image Single cell transcriptomics is a next-generation RNA sequencing approach which allows a high-resolution view of cells. Researchers from University of Southern Denmark, Wellcome Sanger Institute and BGI, published the study in the journal Genome Biology. What is single cell transcriptomics? RNA sequencing uses next-generation sequencing to analyse the presence of RNA in a sample.1,2 According to the University of Southern Denmark, single cell transc... Read More

Genes and Ontogenes in Drosophila: The Role of RNA Forms

Image The goals of genetics are to explore and establish the link between a trait and a heredity factor. In turn, the central dogma of molecular biology posits the flow of genetic information from DNA through RNA to protein, which ultimately forms a trait. In this currently accepted scenario, the genetic system is formed by universal genes that function to produce proteins. Nonetheless, multiple lines of evidence indicate that this is not the sole scenario of how genetic systems may operate. L... Read More

Genetic syndromes-New 2020 Issue

Image Genetic syndromes-New 2020 Issue Journal of Genetic Syndromes & Gene Therapy is an open access publisher which provides scientific information to all the researchers and academicians in all quarters. Journal of Genetic Syndromes & Gene Therapy (JGSGT) brings articles in all areas related to Genetics such as Genetic disorders, Genetic mutations, Auto immune diseases etc on Quaterly basis. JGSGT welcomes... Read More

Gene Mapping

Image Gene Mapping NLM ID: 101574143 Index Copernicus Value 2016: 84.15 The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to genetics. On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of ... Read More

Multiplex Immunohistochemistry: The Importance of Staining Order

Image Immunotherapy: Open Access has recently published an article entitled “Multiplex Immunohistochemistry: The Importance of Staining Order WhenProducing a Validated Protocol” in its volume 5 Issue 2 written by Jihad Syed, Jack Ashton, Jesuchristopher Joseph, Gemma N Jones, Christian Slater, Alan Sharpe,Garry Ashton, William Howat, Richard Byers, Helen K Angell from Institute  of  Cancer  Sciences,  University  of  Manchester,  Manchester,  UK and Translational  Medicine,  Oncology  R&D,&nbs... Read More

Co-expression of PD-L1 Antibodies Enhances the Anti-Tumor Efficacy

Image Chimeric antigen receptor T cell (CAR-T) therapy has shownsignificant efficacy in treating patients with refractory B-cellleukemia and lymphoma [1,2]. However, CAR-T therapy hasyielded less favorable results in treating patients with solidtumors such as pancreatic, ovarian or mesothelioma cancers[3-5]. One of the major obstacles in treating solid tumors withCAR-T is the scarcity of antigen that is uniformly expressed intumor cells such as CD19 in B cell hematologic malignancies[6,7]. Therefore, designing a CAR against an antigen that ishighly expressed in cancer cells but either has negligi... Read More

Immunotherapy: Open access | Call for papers

Image Journal of Immunotherapy: Open access features rapid publication of articles on immunomodulators, lymphokines, antibodies, cells, and cell products in cancer biology and therapy. Laboratory and preclinical studies, as well as investigative clinical reports, are presented. The journal emphasizes basic mechanisms and methods for the rapid transfer of technology from the laboratory to the clinic. IMT contains full-length articles, review articles, and short communications.   Instructions for authors are as follows:   Manuscrip... Read More

Latest Breakthrough in Cell signaling

Image Journal of Cell Signaling brings articles in all areas related to effector systems, such as protein kinases, lipid signaling pathways, cyclic nucleotide signaling processes, NO signaling and ion channels. The production, regulation, degradation and action of second messengers; the structure, regulation, degradation and action of receptors; Guanine nucleotide regulatory proteins; Bio-informatics studies related to cell signaling mechanisms.  A new area for bioscience and clinical rese... Read More

Bioinformatics Market Growing Technology Trends and Business Opportunities by 2025

Image Bioinformatics is the combination of information technology, statistics, molecular biology, and algorithms to analyze the data obtained from various experiments. It includes collecting biological data, preparation of a computational model, solving computational modeling problems, and evaluation of computational algorithm. Bioinformatics uses computation to extract knowledge from biological data, which can be used in drug discovery and developments. The ... Read More

Gene Expression - RNA to protein

Image Gene Expression - RNA to protein Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do?. Moreover, each step in the flow of information from DNA to RNA to protein provides the cell with a potential control point for self-regulating its functions by adjusting the amount and type of proteins it manufactures. At any given time, the amount of a particular protein in a cell reflects th... Read More

Gene Expression

Image Gene Expression Visakhapatnam, 29-11-2019 On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Genetic Syndromes & Gene Therapy. The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on al... Read More

Evolutionary Trends in Gene

Image Evolutionary Trends in Gene Visakhapatnam, 29-11-2019 The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to genetics. On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Geneti... Read More

Cell signalling recent research work

Image On behalf of the  Journal of  Cell Signaling , as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been four years we have started the Journal, now we are celebrating the 4th Anniversary and we are privileged to welcome Analytical Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to the Journal of  Cell Signaling Journal of Cell Signaling brings articles in all areas relate... Read More

Advances in transcriptomics provide insights into brain disease and development

Image In recent years, technological advancements in transcriptomics (the process of studying a cell’s complete set of RNA transcripts) have provided new opportunities for researchers to study brain diseases and development at the single-cell level. This was highlighted by a series of abstracts, all presented recently at the SfN Neuroscience 2019 (Chicago, IL, USA; 19-23 October 2019), where researchers utilized transcriptomics to study the underlying c... Read More

Mechanism of Low Endotoxin Recovery Caused by a Solution Containing a Chelating Agent and a Detergent

Image Mechanism of Low Endotoxin Recovery Caused by a Solution Containing a Chelating Agent and a Detergent Mechanism of Low Endotoxin Recovery (LER) was investigated by observing the change in particle sizes and activity of endotoxin in LER solutions containing sodium citrate and polysorbate 20. Interestingly, endotoxin aggregates were not dispersed to be smaller particles under LER conditions according to the decease of the activity. This observation was different from previous predictions of the mechanism. Endotoxin aggregates were observed by Dynamic Light Scatterin... Read More

About Transcriptomics technologies

Image Transcriptomics technologies are the techniques used to study an organism’s transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription. Here, mRNA serves as a transient intermediary molecule in the information network, whilst non-coding RNAs perform additional diverse functions. A transcriptome captur... Read More

Transcriptomics of Single Cell: New Discoveries to Become Basis for Future Studies

Image Single-cell transcriptome profiling has been an indispensable tool used for determining cell type, transcriptomic signatures, and single cell transcriptomics of ncRNAs. Нis technique could bring about a paradigm shiі in disease management and could even become the basis of further studies. to study the expression levels of mRNAs in a cell. Tra... Read More

New Issue Release 2020 -Journal of genetics syndrome and gene therapy[Upcoming Issue]

Image New Issue Release 2020 -Journal of genetics syndrome and gene therapy[Upcoming Issue] The Journal of genetics syndrome and gene therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics of genetics syndrome and gene therapy We are pleased to deliver the table of contents alert for Journal of genetics syndrome and gene therapy ... Read More

Genetic syndromes

Image Genetic syndromes Journal of Genetic Syndromes & Gene Therapy is an open access publisher which provides scientific information to all the researchers and academicians in all quarters. Journal of Genetic Syndromes & Gene Therapy (JGSGT) brings articles in all areas related to Genetics such as Genetic disorders, Genetic mutations, Auto immune diseases etc on Quaterly basis. JGSGT welcom... Read More

The mTOR Family of Proteins and the Regulation of Trophoblast Invasion by Gas6

Image Journal of Cell Signaling aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to Computer Science and Information Technology. Abstract Objective: Preeclampsia is an obstetric complication wherein trophoblast invasion is decreased and high levels of serum Gas6 protein are present. Our objective was to assess members of the mTOR family that are ... Read More

Cell activity and the signaling pathways

Image Cell signaling is a process through which living cells interact with the cellular environment and neighbouring cells. Cells contain Glycoproteins or Glycolipids as receptors on their plasma membrane which detects the signals. When a complementary ligand (signaling molecule) comes and binds to the receptor, it initiates a chain of reactions within the cell, ultimately leading to a response. Longdom Publishing SL organizes 1000+ conferences every year across U... Read More

Current research on Genetic Syndrome and Gene Therapy

Image Current research on Genetic Syndrome and Gene Therapy The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to genetics. On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Genetic Syndromes & Gene The... Read More

Use of genomics to balance cure and complications

Image Use of genomics to balance cure and complications The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to genetics. The open access journal is published by longdom who hosts around 350 open access peer-reviewed journals as well as organizes more than 100 International scientific Conferences. Jou... Read More

All about Probiotics

Image Probiotics are microorganisms naturally present in the digestive tract that aid in digestion and reduce inflammation. The normal human digestive tract contains about several types of probiotic bacteria that reduce the growth of harmful bacteria and promote a healthy digestive system. The largest group of probiotic bacteria in the intestine is lactic acid bacteria, of which Lac... Read More

Instructions for Authors Regarding Article Submission- Transcriptomics: Open Access

Image Transcriptomics: Open Access (TOA) provides the Half-Yearly publication of articles in all areas related to medical science like Transcripotme,TOA welcomes the submission of manuscripts that meet the general criteria of significance and scientific excellence. Papers will be published approximately one month after acceptance. Submit as an e-mail attachment to the Editorial Office at ... Read More

Recent Research Treads in Cell signalling

Image On behalf of the  Journal of  Cell Signaling , as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been four years we have started the Journal, now we are celebrating the 4th Anniversary and we are privileged to welcome Analytical Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to the Journal of  Cell Signaling. The ... Read More

Journal of Cell signalling providing Discounts on its publication charges

Image Journal of Cell Signaling brings articles in all areas related to effector systems, such as protein kinases, lipid signaling pathways, cyclic nucleotide signaling processes, NO signaling and ion channels. The production, regulation, degradation and action of second messengers; the structure, regulation, degradation and action of receptors; Guanine nucleotide regulatory proteins; Bio-informatics studies related to cell signaling mechanisms; Compartmentalization/compartmentation of signalin... Read More

Rare genetic disorder | Facts & Findings

Image Journal of Genetic Disorders and Genetic Medicine is a OPEN ACCESS peer reviewed journal which publishes Original Articles, Reviews, Case Reports, Clinical Images related to Genetic Disorders, Chromosomal Disorders, Gene Mapping, Gene Therapy genetically birth defects, Cancer Genetics , Genetic Mutations, Metabolic Diseases, Single Gene Disorders, Genetic aspects of Common Complex Diseases, Population Genetics, Environmental Genetics, Genetic Counseling & Education, Gene Regulation, Epigenetics, Disease... Read More

Recent Research on Cell Signaling

Image The Journal of Cell Signaling is a peer reviewed journal. This journal offers an open access platform for authors to publish their research. The Journal of cell signaling is an open access journal which mainly focuses on effector systems, such as protein kinases, lipid signaling pathways, cyclic nucleotide signaling processes, NO signaling and ion channels. The production, regulation, degradation and action of second messengers; the structure, regulation, degradation and action of recepto... Read More

Updated Science on Genetics

Image Updated Science on Genetics NLM ID: 101574143 Index Copernicus Value 2016: 84.15 The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to genetics. On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour t... Read More

Inviting you to Join as an Editorial Board to our Transcriptomics: Open Access Journal

Image Transcriptomics: Open Access is a broad-based journal found on two key tenets: To publish the most exciting research work in fields related to Transcriptomics: Open Access : Second to provide a rapid and quick reviewing and publishing of articles for research, teaching and reference purposes. It is basically aimed at the Clinical Practitioners, medical/ health practitioners, students, professionals and researchers and professional bodies and institutions. &n... Read More

Transcriptomics: Open Access

Image TranscriptLongdom Publishing is a total set of transcripts in a given organism and referred to as an expression profiling that examines the expression level of mRNAs in a given cell population. TranscriptLongdom Publishing includes high-throughput techniques based on DNA microarray. TranscriptLongdom Publishing:Open Access Journal is at higher echelons that enhance the intelligence and information dissemination on topics closely related to TranscriptLongdom Publishing. They provide a uni... Read More

Transcriptomics: Open Access Admires its Editors and Research Scholars for their Great Support Towards the Journal.

Image Transcriptomics: Open Access expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout the publication journey of the journal, right from its inception in the year and congratulates them for making the journal achieve its goals and becoming successful as one of the leading and well-recognized broadcaster of scientific outcomes and perspectives from Transcriptomics globally The journal is extremely pr... Read More

Science Advancements in Gene Expression

Image Science Advancements in Gene Expression Visakhapatnam, 29-11-2019 On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Genetic Syndromes & Gene Therapy. The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topic... Read More

The Origin of Life; Cell activity in living Organism

Image On behalf of the  Journal of  Cell Signaling , as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been four years we have started the Journal, now we are celebrating the 4th Anniversary and we are privileged to welcome Analytical Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to the Journal of  Cell Signaling The Journal is successfully running in the 4th Vol... Read More

Evolutionary Trends in Genetic Syndrome and Gene Therapy

Image Evolutionary Trends in Genetic Syndrome and Gene Therapy Visakhapatnam, 29-11-2019 The Journal of Genetic Syndromes & Gene Therapy aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to genetics. On behalf of the Journal of Genetic Syndromes & Gene Therapy, as Editor-in-Chief, it is my great pleasure and honour to welcome you to the Journal of Genetic ... Read More

Journal of Cell Science & Therapy announce successful 11th anniversary in research publication

Image The editorial team of Journal of Cell Science & Therapy  are overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal and take part in the year-long celebrations. During this year we look forward to taking some initiates that would encourage and reward our prospective customers. It gives us great pleasure in announcing the call for paper on the 11th Anniversary of the Journal at special and hefty discount of ... Read More

Bipolar Disorder: Open Access

Image Bipolar Disorder: Open Access, is an international scholarly, peer reviewed journal in the field of neuropsychopharmacology, neuropathology, genetics, brain imaging, epidemiology, phenomenology, clinical aspects, and treatments of bipolar disorders. Journal expresses its warm gratitude to especially the Editorial Board, and extending this gratitude to all the Authors, researchers, Editors and Students who have contributed their valuable researches in the form of full article, case reports to this journal. The Journal mainly focusses to serve its readers. Journal was started in the... Read More

Spreading knowledge globally, Research on Cell activity

Image Spreading knowledge globally, Research on Cell activity The Editorial Board of Journal of Cell signalling is overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal and take part in the year-long celebrations. During this year we look forward to taking some initiatives that would encourage and reward our prospective audience which include clinicians, research scientists, decision-m... Read More

Cell and Developmental Biology - A Transparent Window to the World of Cells - Journey of 8 Years

Image Cell & Developmental Biology journal has attained a unique identity among journals of cell and development. On this eve, we express our sincere gratitude towards editorial board for their endless support, help and service. It also extends a very warm welcome to all the researchers, scientist and scholars to contribute their latest finding as full length article to this Journal. Cell and Devel... Read More

Mycobacterial Diseases: Accepts Manuscripts for Upcoming Issue

Image Mycobacterial Diseases celebrates more than a decade of its existence in the field of clinical publishing and research and extends a very warm welcome to all the authors, researchers, editors and student to contribute their latest research findings as full length articles to this collaborative health journal. The journal is committed to serve its readers authors by adding the state of the art facilities to enhance the author’s scholarly visibility. Established in the year 2011, Mycobacterial Diseases is one of the most reputed journals of Longdom group, the medical publ... Read More