Skin Disease~ Psoriasis

Image Psoriasis is a common skin condition that speeds up the life cycle of skin cells. It causes cells to build up rapidly on the surface of the skin. The extra skin cells form scales and red patches that are itchy and sometimes painful. Psoriasis is a chronic disease that often comes and goes. The main goal of treatment is to stop the skin cells from growing so quickly. There is no cure for psoriasis, but you can manage symptoms. Lifestyle measures, such as moisturizing, quitting smoking and managing stress, may help. Symptoms Psoriasis s... Read More

Endorsement of New Drugs

Image 1) Zeposia (ozanimod) Capsules Company: Bristol-Myers Squibb Company Date of Approval: March 25, 2020 Treatment for: Multiple Sclerosis Zeposia (ozanimod) is a sphingosine 1-phosphate receptor modulator indicated for the treatment of relapsing forms of multiple sclerosis (MS).   2) Isturisa (osilodrostat) Tablets Company: Novartis Pharmaceuticals Corporation Date of Approval: March 6, 2020 Treatment for: Cushing's Syndrome Isturisa (osilodrostat) is a cortisol synthesis inhibitor ind... Read More

How Are Contagious diseases are Transmitted?

Image Overview Infectious diseases are transmitted from person to person by direct or indirect contact. Certain types of viruses, bacteria, parasites, and fungi can all cause infectious disease. Malaria, measles, and respiratory illnesses are examples of infectious diseases.   Simple preventative measures, such as frequent hand washing, can cut down on disease transmission.    Direct contact Infectious diseases are often spread through direct contact. Types of direct contact include:    1. Per... Read More

Fresh access towards the medication of Contagious Diseases

Image The problem of antibiotic resistance in bacteria has reached the crisis stage. Coincident with ever-increasing rates of resistance to conventional antibiotics is the slowing in development of novel-acting antibiotics by the pharmaceutical industry. The convergence of these trends has led to the relatively common occurrence of multidrug- and extensively drug-resistant bacteria. The World Health Organization recently reported that “a postantibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibi... Read More

NF-kB Pathway Antibodies

Image Author Name: Keith Howell Category Name: Medical science Description: Nuclear Factor kappa-light-chain-enhancer of activated B cells or NF-κB  is found in almost all animal cells and is a protein complex that controls the transcription of DNA. This protein complex is involved in numerous cellular responses and plays a key role in regulating the immune response to infection. NF-&kappa... Read More

Apoptosis Pathway Antibodies

Image Author Name: Keith Howell Category Name: Medical science Description: In highly organized biological systems like multicellular organisms, tight regulation of growth and death is imminent. If cells are no longer required, they commit suicide by activating an intracellular death program. This method of programmed cell death is called apoptosis (from Ancient Greek ἀπόπτωσ&iota... Read More

Etiology

Image When a doctor tries to figure out the cause of a disease, they are actually trying to figure out the etiology of the disease. Etiology is the cause of a disease or the science that deals with such causes. The word etiology comes from the Greek etio-, which means 'causation' and -ology, which refers to the scientific study of something. You might be familiar with similar terms such as biology and geology. These words also refer to the scientific study of something. Biology is the study of life (... Read More

IMMULITE ® Technology

Image The heart of IMMULITE 1000 is the proprietary Test Unit, which offers a breakthrough in automated bead washing. The Test Unit, containing an assay-specific coated bead, serves as the reaction vessel for all sample processing. Spinning the Test Unit at high speed efficiently expels fluid into the integral sump chamber. The tube design allows for multiple discrete washes within seconds, ensuring excellent separation of unbound material for highly sensitive assays. IMMULITE 1000's unique wash technique produces extremely low and consistent nonspecific binding, which is critical for assay ... Read More

Tetanus: Case Report, Epidemiology

Image To  describe  a  rare  case  with  generalized  tetanus  to  reinforce  the  relevance  of  early  detection  and management. Case report: A 38 year old Pakistani man presented with neck stiffness to the emergency room 12 d after he had trivial nail injury to his foot for which he didn’t need to seek any medical advice. Tetanus was diagnosed based on clinical symptoms and history. The management consist of antibiotics therapy with penicillin-metronidazole, tetanus toxoid and tetanus imm... Read More

Radical Prostatectomy

Image Prostatic adenocarcinoma (PCa) is one of the major contributors to malignancy in men worldwide and second leading cause of cancer death after lung cancer. PCa is an aggressive disease and shows a strong predilection to metastasize into the bones and pelvic lymphatic nodes. In contrast, the metastatic spreads into testicles are rare, accounting up to 4% of all prostate cancer (PCa) cases. Here we present a case from our practice of unilateral testicular metastasis, developed secondary to prostatic carcinoma and diagnosed 6 months after radical prostatectomy. A 69-year-old man presented to ou... Read More

Rogue cells at root of autoimmune disease

Image Author Name: Keith Howell Category Name: Medical science Description: There are more than 100 different autoimmune diseases. But what unites them all is that they arise from an individual's own cells rare and mysterious immune cells that target not external viruses and bacteria but the body's own healthy organs and tissues. For the first time, Researchers have pinpointed individual cells that cause autoimmune disease from patient samples. They also uncovered how these cells 'go r... Read More

Timing of immune response to COVID-19 may contribute to disease severity

Image Author Name: Keith Howell Category Name: Medical science Description: A new USC study suggests that temporarily suppressing the body's immune system during the early stages of COVID-19 could help a patient avoid severe symptoms. An interaction between the body's two main lines of defense may be causing the immune system to go into overdrive in some patients. The body'... Read More

Diagnosis ofInvasive Aspergillosis using Galactomannan nd (1-3)-Beta-D-Glucan Assays

Image   Invasive Aspergillosis is an opportunistic mycotic infection witha mortality rate of 15-30% depending on when the infection isdiagnosed and type of therapy elected. While therequirement for a diagnosis of proven invasive pulmonaryaspergillosis remains a lung biopsy for histopathology andculture, these patients are immunocompromised by definitionand such an invasive procedure is often not recommended. Empiric treatment, likewise, is not ideal because the an... Read More

Otomastoiditis- Pneumococcus as Leading Cause, and High Impact of Pneumococcal 13-Valent Conjugate Vaccine

Image   We have published several studies related to Invasive Pneumococcal Disease, and effectiveness of Pneumococcal Conjugate Vaccines: 7-valent (PCV7) and 13-valent (PCV13). This is the first Latin American, prospective study looking for Otomastoiditis (OM) in children, and the impact of PCV13 on this disease. Methods: Since October/1st/2005 until September/30th/2017, prospective surveillance to identify all children<16 years old with OM at the Tijuana, Mexico, General Hospital was performed. OM was diagnosed with otoscopy, and tomographic signs of ... Read More

Separation of Mixtures of Chiral Compounds by their Distribution between Different Phases

Image The function of living organisms is determined by the behavior of chiral compounds and their reactions. Not only the RNA and DNA influence this function, but the enantiomers of amino acids and sugars also have a dominant role. So, it is not surprising that an increasing number of drugs contain single enantiomers, which are often prepared by resolution of racemic compounds obtained due of chemical syntheses. The therapeutically effect of enantiomers can be different, and it is not rare that these effects are opposite. A tragic reminder of the importance of chirality is thalidomide,... Read More

Development of High-performance Thin-layer Chromatography

Image High-Performance Thin Layer Chromatography (HPTLC) is a reliable and rapid method useful for the detection of product quality and composition. In recent times, HPTLC instrumentation allows to obtain fingerprints suitable to determine composition and identity of plant raw materials. This study aimed at exploring the results of High-performance Thin Layer Chromatography (HPTLC) analysis as a useful means for the authentication of Allanblackia parviflora kernel and seed oils using the fingerprint approach. Sixteen bulked kernel and seed oil samples from 16 different communities were a... Read More

Schistosomiasis and Soil Transmitted Helminthiases

Image   With delayed treatment, schistosome and soil transmitted helminth (STH) infections in young children (<5 years)could potentially lead to irreversible lifelong detrimental health effects. This is because these infections are known tocause suboptimal growth and development in this critical phase of life. The present study sought to document theburden of schistosome and STH infections in Taita Taveta County, Kenya, by determining the prevalence andintensity of the infections in children less than 5 years of age. The study al... Read More

Cross-Reactivity Measurement of Cashew Nut, Hazelnut and Peanuts

Image   Tree nut allergic individuals are often sensitised towards multiple nuts and seeds. The underlying cause behind a multi-sensitisation for cashew nut, hazelnut, peanut and birch pollen is not always clear. We investigated whether IgE cross-reactivity between cashew nut-, hazelnut- and peanut proteins exists in children that are multi-allergic to these foods using a novel IMMULITE®-based inhibition methodology, and investigated which allergens might be responsible. In addition, we explored if an allergy to birch pollen might play a role in this cosensitisatio... Read More

Human Sport Doping Control Analysis is a Complex and Challenging Task for Anti-Doping Laboratories

Image Human doping refers to the use of performance-enhancing drugs by the athletes. Human sport doping control analysis is a complex and challenging task for anti-doping laboratories. The field is regulated by the World Anti-Doping Agency (WADA), whose aim is to achieve globally harmonized results and equal treatment for all athletes. The List of Prohibited Substances and Methods is updated annually by WADA and consists of hundreds of chemically and pharmacologically different low and high molecular weight (MW) compounds. In sports, today the aim is to provide equal opportunities for a... Read More

Rapid Optical Detection Strategy for Human Pathogens

Image Quick, sensitive and specific detection of infectious agents can aid in better treatment of patients and forrecognition of contaminants. Traditional methods suffer from drawbacks of being time consuming and tedious toperform and modern medicine advances call for better detection methods. Strategies employing nanoparticle basedsystems are under investigation to allow for efficient and rapid detection of pathogenic microorganisms.Nanoparticles have been conjugated with nucleic acid probes and antibodies to serve as one step detection system,based on conserved genomic DNA sequences and specifi... Read More

Need for Reference Ranges

Image Reference data for clinical chemistry on reference values of children in Taita Taveta County are fundamental for clinical diagnosis, management and research. In such a study, a target sample population of 120 respondents is usually required. In this study, a total of 577 healthy subjects from Taita Taveta population were employed to generate the normal reference data on eight clinical chemistry markers. The data obtained will provide needed information to medical practitioners with regards to patient management, as well as conducting research studies on disease.... Read More

Single-molecule nanomechanical mass spectrometry

Image Nanoelectromechanical systems (NEMS) are enabling important emerging applications in diverse fields ranging from quantum measurement to biotechnology. In general, the smaller a device, the more susceptible are its physical properties to perturbation by external influences. This enhanced sensitivity of NEMS is opening a variety of unprecedented opportunities for applications such as mass spectrometry, which is now widely used for proteomics. Furthermore, to reliably detect the expression of low-level signals and to understand the fundamental biological processes, it is important to develop t... Read More

New and Emerging Analytical Techniques for the Detection of Organic Contaminants in Water

Image Detailed chemical analysis of water is a prerequisite for assuring the safety of water supplies. Limitations in our ability to identify contaminants in water also limit our ability to assure water quality and to assess environmental impacts. Recent improvements in analytical techniques have expanded the "analytical window," that is, the compound range that is amenable to specific identification. Using these improved tools, much has been learned about the occurrence, fate, and transport of organic chemicals in the environment. The boundaries of the analytical window represent the &... Read More

CRISPR corrects genetic defect so cells can normalize blood sugar

Image Author Name: Keith Howell Category Name: Medical science Description: The findings, from researchers suggest the CRISPR-Cas9 technique may hold promise as a treatment for diabetes, particularly the forms caused by a single gene mutation, and it also may be useful one day in some patients with the more common forms of diabetes, such as type 1 and type 2. Patients with Wolfram syndrome devel... Read More

Neuropathogenic Coronaviral Infection

Image   Murine coronavirus, mouse hepatitis virus (MHV), causes various diseases depending on the strain and route of inoculation. Both the JHM and A59 strains, when inoculated intracranially or intranasally, are neurovirulent. Comparison of the highly virulent JHM isolate, JHM.SD, with less virulent JHM isolates and with A59 has been used to determine the mechanisms and genes responsible for high neuropathogenicity of MHV. The focus of this review is on the contributions of viral spread, replicati... Read More

Kind of Signals Do Cells Receive

Image Author Name: Keith Howell Category Name: Medical science Description: Most cell signals are chemical in nature. For example, prokaryotic organisms have sensors that detect nutrients and help them navigate toward food sources. In multicellular organisms, growth factors, hormones, neurotransmitters, and extracellular matrix components are some of the many types of chemical signals cells use. These sub... Read More

biological systems using lipidomics

Image The mass spectrometry (MS) resources on campus aim to provide researchers with state-of-the-art techniques and equipment to characterize biomolecules including proteins and peptides (proteomics, sugars including glycoproteins (glycemic), metabolites (metabolomics) and lipids (lipidomics). A number of state-of-the-art instruments for the separation of biomolecules and their analysis by mass spectrometry-based approaches are available. In addition to providing analytical services, the mass spectrometry facility on campus provides training to on-campus scientific staff on the use of this techn... Read More

Cell Signaling: Architectural Beauty and Complexity

Image Author Name: Keith Howell Category Name: Medical science Description: A clear theme that emerges is the enormous complexity that underlies most cellular responses and the vast variety of proteins and interaction/binding motifs used to transduce signals. The extent of complexity is particularly surprising when one considers that as recently as the late 80s and early 90s many believed that all cellula... Read More

Psoriasis

Image   Psoriasis is a common skin condition that speeds up the life cycle of skin cells. It causes cells to build up rapidly on the surface of the skin. The extra skin cells form scales and red patches that are itchy and sometimes painful. Psoriasis is a chronic disease that often comes and goes. The main goal of treatment is to stop the skin cells from growing so quickly. There is no cure for psoriasis, but you can manage symptoms. Lifestyle measures, such as moisturizing, quitting smoking and managing stress, may help. Symptoms ... Read More

Electrokinetic Treatment Technique for Improving the Engineering Characteristics of Low Permeable Problematic Soils

Image In recent years, major settling or tilting of buildings and bridges, instability of dams and road embankments have been observed and many attempts have been made in order to mitigate such damages. In this regard, it is necessary to determine the soil improvement alternatives, technically and economically, from the ultimate state design in accordance with geotechnical categories, to stabilize and remediate the existing soft problematic soils prior to the commencement of any construction activities. The aims of improving soils (as foundation and construction materials) are to increase strengt... Read More

Hepatitis-B

Image Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). It is a major global health problem. It can cause chronic infection and puts people at high risk of death from cirrhosis and liver cancer. A safe and effective vaccine that offers a 98-100% protection against hepatitis B is available. Preventing hepatitis B infection averts the development of complications including the development of chronic disease and liver cancer. Transmission In highly endemic areas, hepatitis B is most commonly spread from... Read More

Old human cells rejuvenated with stem cell technology

Image Author Name: Keith Howell Category Name: Medical science Description: Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of proteins involved in embryonic development. The researchers also found that elderly mice regained youthful strength after their existing muscle stem cells were subjected to the rejuvenating protein treatment and... Read More

COVID-19 coronavirus epidemic has a natural origin

Image Author Name: Keith Howell Category Name: Medical science Description: The analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered. By comparing the available genome sequence data for known coronavirus strains, we can firmly determine that SARS-CoV-2 originated through natural processes In ... Read More

Pharma Unlike FDA, European regulators refuse to clear chloroquine for COVID-19 without data

Image Chloroquine and hydroxychloroquine have drawn more attention—and certainly more presidential support—than any other drug during the global quest to find an effective coronavirus therapy. Now, days after the FDA gave them an emergency approval to treat COVID-19, European regulators are limiting their COVID-19 use to clinical trials only. The decision comes as limited data—some of it questionable—rolls in about the drugs and their potential as COVID-19 therapies. A French study that's made headlines continues to draw fire, bu... Read More

COVID-19 is bad news for new drug launches. Which will suffer most?

Image The COVID-19 pandemic and the ensuing societal countermeasures are upending operations in many sectors—and biopharma isn't immune. The current lockdown is not only hurting clinical trial enrollment but also delaying regulatory timelines for drugs nearing a decision. And with tried-and-true, in-person marketing techniques no longer allowed, new launches may also feel the pain—or hold off altogether. Consider Bristol Myers Squibb and its big new approval for multiple sclerosis drug Zeposia. It's a long-awaited med, but BMS is postponing the launch under... Read More

Cell Signaling :CRISPR gene cuts may offer new way to chart human genome

Image Author Name: Keith Howell Category Name: Medical science Description: The researchers say that pairing CRISPR with tools that sequence the DNA components of human cancer tissue is a technique that could, one day, enable fast, relatively cheap sequencing of patients' tumors, streamlining the selection and use of treatments that target highly specific and personal genetic alterations.For tumor seq... Read More

New Drugs Approval

Image   1) Zeposia (ozanimod) Capsules  Company: Bristol-Myers Squibb Company  Date of Approval: March 25, 2020  Treatment for: Multiple Sclerosis  Zeposia (ozanimod) is a sphingosine 1-phosphate receptor modulator indicated for the treatment of relapsing forms of multiple sclerosis (MS).  2) Isturisa (osilodrostat) Tablets  ... Read More

New approaches for treatment of Infectious Diseases

Image The problem of antibiotic resistance in bacteria has reached the crisis stage. Coincident with ever-increasing rates of resistance to conventional antibiotics is the slowing in development of novel-acting antibiotics by the pharmaceutical industry. The convergence of these trends has led to the relatively common occurrence of multidrug- and extensively drug-resistant bacteria. The World Health Organization recently reported that “a postantibiotic era—in which common infections and minor injuries can kill—far from being an apocalypt... Read More

Probiotics in clinical practice

Image The interaction of the gastrointestinal microflora with the human host has been the subject of considerable debate in the last decade. Manipulation of the enteric microflora with probiotic organisms has been attempted in a wide range of clinical settings, in the hope of achieving health benefits in the host. This review presents the evidence f... Read More

Relationships between Anti-mullerian Hormone, Testosterone, Luteinizing Hormone and Follicle Stimulating Hormone in Men on Testosterone Therapy

Image Clinical & Medical Biochemistry journal is a scholarly Open Access journal maintains high standards of scientific excellence and its editorial board promises a rapid peer review process with the help of the Editorial Manager System. The Journal publishes original scientific and specialized articles on all aspects of clinical and medical biochemi... Read More

Emergent needle decompression for tension pneumothorax resulting in life threatening intercostal artery injury

Image Journal of Perioperative Medicine aims to promote publications from anesthesia care providers who are otherwise unable to access other journals. Most importantly, those anesthesia care providers from countries or regions that have few resources to provide anesthesia care or approaches to perioperative medicine now have a forum to publish their approaches, research, and dilemmas in patient management. Journal of Perioperative Medicine provides a broader platform t... Read More

A Pediatric Perspective on Stem Cells: Expression, Function and Clinical Relevance

Image In the last ten years, placenta, fetal membranes (i.e. amnion and chorion), and amniotic fluid have been extensively investigated as a potential non-controversial source of stem cells. They are usually discarded after delivery and are accessible during pregnancy through amniocentesis and chorionic villus sampling. Several populations of cells with multi-lineage differentiation potential and immunemodulatory properties have been isolated from the human placenta and fetal membranes; they have been classified by an international workshop as human amniotic epithelial cells (hAECs) [human amniot... Read More

The Role of GroE Chaperonins in Developing Biocatalysts for Biofuel and Chemical Production

Image As the need and interest for producing renewable biofuels and biochemical has grown, new avenues to improve product yields and productivity have been explored. Specifically, improving the tolerance of host microbes towards stressors, such as heat shock or the presence of harmful solvents, has been an especially important route to improve industrial-scale chemical production. In this review, we discuss recent advances in microbial engineering for renewable chemical production through the introduction and expression of chaperonins, especially the bacterial GroE complex. The GroE com... Read More

Insights to Ultrasound Technology

Image  An ultrasound scan finds its applications in medical and research field . The ultrasound technology uses high-frequency sound waves to create images of the internal organs of the body. The major benefit of ultrasound is it does not utilize or emit any radiation that causes harm to the human body. Thus it is also suitable for use during pregnancy.An ultrasound is recommended for heart, kidneys, bladder, brain (in infants), eyes, liver, ovaries, pancreas, spleen, thyroid and other body organs. Another important application of ultrasound is found under water where ... Read More

The Role of Enzymes in Metabolism

Image Metabolism is chemical reactions occurring in organisms. Without enzymes metabolism wouldn’t be fast enough to support life. Metabolism refers to all the chemical reactions occurring in organisms. Chemical composition: Enzymes are made of protein. Protein consists of one or more polypeptide chain. These are made of long chains of amino acids connected by peptide bonds. Structure of Enzymes: In enzymes, the polypeptide chain is folded into a 3D shape. A par... Read More

Role of Enzymes in Detergents

Image The original idea of using enzyme as detergents was described in 1913 by Dr Otto Rohm, who patented the use of crude pancreatic extracts in laundry pre-soak compositions to improve the removal of biological stains. In the same year, the first enzymatic detergent named Burnus was launched, but was not popular because of its own limitations. Subsequently, Bio- 40 - a detergent containing a bacterial protease was produced in Switzerland and launched in the market in1959 and it gradually became popular. In the period from 1965 to 1970, use and sale of detergent enzymes grew very fast. ... Read More

Recent Advances in Clinical Enzymology

Image The past year has seen a wider application of knowledge originating over the last decade rather than startling new developments. For brevity, only serum enzymes will be considered and the points at which progress is being made are indicated by the sectional headings which follow. ENZYME METHODOLOGY: Considerable change is taking place in established enzyme methods and new forms of methodology are being developed. Colorimetric kinetic assays Together with the familiar ultraviolet (UY) kinetic assays, newer kinetic assays utilising wavelengths in the visi... Read More

Call for Research Papers-Enzyme Engineering

Image Enzyme Engineering [EEG] is a peer-reviewed journal that offers researchers and scholars in-depth useful reviews and research trials and surveys of new and novel approaches in the field of Enzymology and Clinical Sciences. Each peer-reviewed issue assesses practice issues; practice settings; therapeutics issues; disease management; the latest research; as well as issues arising from today’s emerging health-care research. Journal Aim... Read More

Nursing, Education and Perioperative Care

Image Journal of Perioperative Medicine is an open access journal that publishes highly topical clinical research relating to the perioperative care of surgical patients. Its essence is the distillation, examination and application of clinical evidence to improve surgical outcome. Modern perioperative medicine is a true multidisciplinary speciality and the journal welcomes research in all areas relevant to perioperative medicine from any healthcare professional. ... Read More

Scope and Growth of Perioperative Medicine

Image   Perioperative medicine encompasses the care of the patient preparing for, having and recuperating from surgery. In the practice of perioperative medicine the surgeon, anaesthesiologist , intensivist and medical consultant work in concert. The medical knowledge distinct to this field includes that of operative risk and complications, of patient specific risks, of methods to reduce risk, and of the management of medical illness during this time period. Evide... Read More

Clinical and Medical aspects of Biochemistry

Image Journal of Clinical and Medical Biochemistry (cmbo) is a journal which publishes original research communications, review articles, case reports, letters to the editor in the field of medical biochemistry and laboratory medicine. The objective of the journal is to publish novel information leading to a better understanding of biochemical mechanisms behind the pathogenesis, diagnosis, and management of human diseases. ... Read More

Biochemistry and Medical Science

Image Medical Biochemistry is a branch of medicine that represents a unique integration of basic biochemical science and clinical medicine. In addition to acting as an effective consultant for clinical colleagues, medical biochemists are trained with the knowledge and skills necessary to operate and manage clinical biochemistry laboratories. The practice of medical biochemistry is privileged to be in tertiary care centres’, as part of a multidisciplinary team including scie... Read More

Applications of Enzymes in Our Daily Life

Image Here are some examples of enzyme biotechnology you might use every day in your own home. In many cases, the commercial processes first exploited naturally occurring enzymes. However, this does not mean the enzyme(s) being used were as efficient as they could be.With time, research, and improved protein engineering methods, many enzymes have been genetically modified. These modifications allow them to be more effective at the desired temperatures, pH, or other manufacturing conditions typically unsuitable for enzyme activity (e.g. harsh chemicals). They are also more applicable and efficient... Read More

Enzyme Engineering: Explore your Research Work-New Edition

Image Enzyme Engineering [EEG] is a peer-reviewed journal that offers researchers and scholars in-depth useful reviews and research trials and surveys of new and novel approaches in the field of Enzymology and Clinical Sciences. Like the Anesthesia research, topics are diverse. Recent topics have included focussing on Enzyme Research: Bioprocess Cross Linking Enzyme Expression Enzyme Kinetics Insilco Design of Enzymes... Read More

Medical Biochemistry and Its Applicative Arm

Image The Journal of Clinical and Medical Biochemistry publishes original scientific and specialized articles on all aspects of clinical and medical biochemistry, molecular medicine, clinical haematology and coagulation, clinical immunology and autoimmunity, clinical microbiology, virology, clinical genomics and molecular biology, genetic epidemiology, drug measurement, evaluation of diagnostic markers, ... Read More

Development and testing of perioperative medicine

Image Journal of Perioperative Medicine (JPME) is an open access journal that publishes highly topical clinical research relating to the perioperative care of surgical patients. Its essence is the distillation, examination and application of clinical evidence to improve surgical outcome. Modern perioperative medicine is a true multidisciplinary speciality and the journal welcomes research in all areas relevant to perioperative medicine from any healthcare professional. ... Read More

New Trends in Journal of Developing Drugs

Image Journal of Developing Drugs is an open access publishing that aims to focus on the Drugs, and also related to Chemistry and Pharmacy. Journal of Developing Drugs deals with chemical compounds found in Drugs that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery and drug design. Articles such as original research papers, review articles, short communications, case reports and commentaries are welcome. Articles related to Drug Metabolism, Drug Designing, Clinical Trails, Drug Discovery, Biopharmceutics, Pharmacokinetics and Pharmacodynamic... Read More

Enzymes and its Role

Image Enzymes are known to catalyze more than 5,000 biochemical reaction types.Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Enzymes are sensitive to external conditions and therefore have unstable characteristics. High temperature, strong acid, alkali and some heavy metal ions will lead enzyme to lose activity and useless. Enzymes are generally difficult to preserve, which brings great difficulties to a wide range of applications. According to the function of the enzyme, enzymes are usual... Read More

Enzymes and its Evolution

Image Enzyme is a kind of catalytic protein produced in the body, functioning as a catalyst. The catalyst can accelerate the chemical reaction without the change of amount and chemistry after the chemical reaction. All enzymes are macromolecules made up of many amino acids with a molecular weight between 10,000 and 1,000,000. Natural enzyme molecules include simple enzymes and binding enzymes. The former molecular composition contains only protein, the latter contains non-protein components, as well as protein composition. Some also contain metal ions. Non-protein components in enzymes ... Read More

Biomedical Research: Grab and bag huge citations with BMR

Image Biomedical Research: Grab and bag huge citations with BMR Biomedical Research (BMR) is a peer-reviewed journal that offers researchers and scholars in-depth useful reviews and research trials and surveys of new and novel approaches in the field of Biological and medical sciences. Like the biomed research, topics are diverse. Recent topics have included focussing on Thyroid Research: Goiter Graves’ Dis... Read More

The Infinite Possibilities of Enzyme Engineering

Image Protein engineering is a powerful tool in synthetic biology that can create proteins with tremendous potential for therapeutic and industrial use. The field has recently taken giant leaps forward from its origins, and some of its pioneers predict that the next five to ten years hold exponentially more promise. Early protein engineering was what David Baker, Ph.D., director of the Institute for Protein Design at the University of Washington, called “Neanderthal protein design.” “You’d look around in nature for something where you could make a couple of amino acid subs... Read More

Applications of Enzyme Engineering for Better World

Image Engineered proteins can be used to optimize desired traits in plants; even though recent advances have resulted in new application areas, certain methodological challenges remain. Protein engineering and directed evolution are powerful technologies for probing protein sequence-function relationships. These methods have been used to engineer both plant-derived proteins and exogenous proteins heterologously expressed in plants. In this review, we aim to further increase the interdisciplinary crossover between the disciplines of protein engineering and plant biology by first introduc... Read More

Resveratrol and Breast Cancer (STUDY)

Image Researchers demonstrate that resveratrol, the ingredient which is found in red wine, prevents the growth of breast cancer cells by stopping the growth effects of estrogen. These study results suggest that resveratrol is capable of counteracting the malignant progression as it suppresses the spreading of hormone resistant breast cancer cells. The discovery has significant implications for treating breast cancer in women whose tumors at some point develop a resistance to hormonal therapy. The researchers made use of a number of breast cancer cell lines that express the est... Read More

Type 2 Diabetes Drugs and Pancreatic Cancer Association

Image According to a study, 2 drugs made use of for treating type 2 diabetes may be associated with a significantly higher risk of the development of pancreatic cancer and pancreatitis, and 1 of the drugs may be associated with an increased thyroid cancer risk. Researchers analyzed the FDA’s database for adverse events reported by individuals making use of the type 2 diabetes drugs exenatide and sitagliptin. A 6 times the increase in the odds ratio for reported pancreatitis cases with these drugs was found, in comparison to 4 other diabetes control therapies. It was also found that individu... Read More

Call from Enzyme Engineering: Open-Access (Volume 8: Issue: 2)

Image Enzymes have played an important role in many aspects of life since the dawn of time. In fact they are vitally important to the existence of life itself. Civilizations have used enzymes for thousands of years without understanding what they were or how they work. The French chemists Anselme Payen and Jean-Franois Persoz described the isolation of an amylase complex from germinating barley and named it diastase. Like malt itself, this product converted gelatinized starch into sugars, primarily ma... Read More

Join our Editorial Board - Chemotherapy: Open Access

Image Chemotherapy: Open Access (CMT) [ISSN: 2167-7700, Index Copernicus Value: 62.73] is one of the best Open Access journals publishes the relevant and reliable information on the discoveries and current developments and all other areas of the field and making them freely available online without any restrictions or any other subscriptions to researchers worldwide. The journal provides multi-disciplinary interpretati... Read More

Chemotherapy: Open Access - Call for Papers

Image Chemotherapy: Open Access (CMT), is one of the best Open Access journals publishes the relevant and reliable information on the discoveries and current developments in the form of original articles, review articles, case reports, short communications, etc. and all other areas of the field and making them freely available online without any restrictions or any other subscriptions to researchers worldwide. Journal expresses its warm gratitude to e... Read More

Call to Join as Editorial Board Member :Enzyme Engineering|Open-Access

Image Our Journal Enzyme Engineering (Longdom Publishers SL) is an esteemed Monthly, Peer reviewed and Open-Access journal that focuses on recent innovative inventions and recent advancements in the field of enzymology and enzyme engineering. Our journal promulgates all current issues that take place in betterment in the field of Life sciences. The ... Read More

Types of Chemotherapy - Chemotherapy: Open Access (Special Edition)

Image Antitumor Antibiotics Antitumor antibiotics are chemo treatments made of natural merchandise made by species of the soil plant life actinomycete.  These medication act throughout multiple phases of the cell cycle and are thought of cell-cycle specific.  There are many forms of growth antibiotics: Anthracyclines: antibiotic, Daunorubicin, Epirubicin, Mitoxantrone, and Idarubicin. Chromomycins:  Dactinomycin and Plicamycin. Alkylating Agents Alkylating agents are most active wit... Read More

Invitation for Article Submission - Chemotherapy: Open Access

Image [ISSN: 2167-7700 | Index Copernicus Value: 62.73] Greetings from Chemotherapy: Open Access! Chemotherapy: Open Access is a prestigious Journal publishing Cancer and Chemotherapy research Articles. This unique Journal aims to publish complete and reliable source of information on the discoveries and current developments in the field of Cancer and Chemotherapy. Journal deals with various types of therapeutic techniques such as Cytotoxic, Electro, and ... Read More

Pancreatic Disorders Journal Aiming at Pancreatitis

Image On behalf of the Pancreatic Disorders & Therapy, as Editor, it is my distinct honour and privilege to inform you that, it’s been eight years we have started the Journal, now we are celebrating them 8th Anniversary and we are privileged to welcome researchers of pancreatic Disorders to our journal. As Editor it is my great pleasure and honour to welcome you to the Pancreatic Disorders & Therapy. The Journal of Pancreatic Disorders & Therapy  a... Read More

Disorders in Pancreatics & Therapy

Image Pancreatic Disorders & Therapy is a peer reviewed medical journal that includes a wide range of topics in this field and creates a platform for the authors to contribute towards the journal. The editorial office promises to peer review the submitted manuscripts to ensure quality PDT is one of the best open access journal that aims to publish the most complete and reliable source of information on discoveries and current developments in the mode of original articles, revi... Read More

Recent Trends in Enzyme Engineering

Image Our Journal Enzyme Engineering (Longdom Publishers SL) is an esteemed Monthly, Peer reviewed and Open-Access journal that focuses on recent innovative inventions and recent advancements in the field of enzymology and enzyme engineering. Our journal promulgates all current issues that take place in betterment in the field of Life sciences. The ... Read More

Journal of Depression and Anxiety accomplished 8 Years Milestone in Research Publication Journey

Image Journal of Depression and Anxiety glad to invite eminent researchers to submit their valuable research for the final issue of Volume 8 in the year 2019. On-behalf of our editorial board we welcome original research, review, case reports, opinions, editorial, image articles, commentary articles covering treatment of depression, anxiety, mood disorders, psychology, pharmacology related to depression. Key topics includes Depression, Anxiety, Menta... Read More

Chemo and Cancer Therapies: Part 1

Image Chemotherapy: Open Access takes privilege to share the topics related to types of Chemo and Cancer Therapies. Chemotherapy (CMT) is one of the best Open Access journals publishes the relevant and reliable information on the discoveries and current developments in the form of original articles, review articles, case reports, short communications, etc. and all other areas of the field and making them freely available online without any restrictions or any other subscript... Read More

Advanced treatments in Chemotherapy

Image A vast body of research, collected over decades, has confirmed that chemotherapy (or radiotherapy) alone is not sufficient to destroy neoplastic lesions completely. The standard routine now implemented in most hospitals is that of combining chemotherapy and/or radiotherapy alongside immunotherapies. In essence, immunochemotherapy refers to the treatment and management of disease by combining immunotherapy with chemotherapy. The goal of this combination is to ... Read More

Journal of Enzyme Engineering Celebrating its Success Journey of 8 years By Annunciating Discounts on Article Processing Charges

Image Enzymes are known to catalyse more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction rate by lowering its activation energy. Some enzymes can make their conversion of substrate to product occur many millions of times faster. An extreme example is orotidine 5'-phosphate decarboxylase, which allows a reaction that would otherwise take millions of ... Read More

Engineering Practices in Enzymes in Daily Life

Image Enzymes are both proteins and biological catalysts (biocatalysts). Catalysts accelerate chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyse individual steps. The study of enzymes is called enzymology&nbs... Read More

Advanced Techniques in Biology & Medicine-Successful Journey

Image Advanced Techniques in Biology & Medicine has effectively finished its seven volumes and effectively going into the eightby 2020. On this event we heart completely welcome researchers, academicians, students and research scholars to distribute their exploration discoveries as Research articles, Case reports, Reviews, Perspectives, Short editorials and so on., towards this Journal at most elevated potential limits and top tier services. The journal has ta... Read More

More you should know about Chemotherapy: Open Access

Image Chemotherapy: Open Access takes privilege to share information with our readers about our Editorial Board members along with First and foremost Editor-in-Chief Tetsuya Konishi Professor, Department of Functional and Analytical Food Sciences. Niigata University of Pharmacy & Applied Life Sciences, Japan. Who is supporting and contributing his valuable time since long time with our Journal. Chemotherapy: Open Access Journal is honour ... Read More

Let’s have a look at Chemotherapy: Open Access

Image Chemotherapy: Open Access is an Open Access journal that aims to publish quality articles by following stringent peer review process. The main motto of the journal is to disseminate the research knowledge worldwide shared by the Scientific Experts in the form of Research Article, Review Article, Case reports, Short Commentary, etc. The purpose of publishing excellent research information is to create a huge impact on aspiring researcher across the globe. Chemotherapy: ... Read More

On Completing Decade of Successful Publishing Journal of Neonatal Biology Announces Special Issue-Care of the infant affected by Neonatal Abstinence Syndrome

Image Journal of Neonatal Biology (ISSN: 2167-0897) is scheduled to celebrate its 9th anniversary in the year 2020. The monthly journal has successfully released several issues of peer-reviewed articles collated from wide geographic locations across the world since its inception in the year 2012, in addition to several special issues. To commemorate the decade long publications services, the editorial team of the journal is planning to compile an edited special issue focusing on tending research activities in Neonatal. The theme/t... Read More

Endocrinology & Metabolic Syndrome

Image Endocrinology & Metabolic Syndrome Accomplished 8 Years Milestone in Research Publication Journey Endocrinology & Metabolic Syndrome celebrates its 8 years of existence in the field of medical research publication and extends a very warm welcome to all the authors, researchers, editors and students across the world to contribute their latest research findings as full-length articles to this collaborative medical journal. Endocrinology & Metabolic... Read More

Journal of Osteoporosis and Physical Activity Marks Its Nine Long Years of Journey by Announcing Hefty Discounts on Article Processing

Image Journal of Osteoporosis and Physical Activity is established in the year of 2013 publishes updated scholarly information on osteoporosis from wide range of geographies across the world. During this year we look forward to taking some initiates that would encourage and reward our prospective customers. Journal of Osteoporosis and Physical Activity provides the quarterly publication of articles in all areas related to Osteoporosis like ... Read More

Annals and Essences of Dentistry Celebrates More Than a Decade of Medical Research Publication

Image The journal welcomes write-ups for possible publication in the form of original research articles, review articles, and clinical studies from all the relevant subject categories. Annals and Essences of Dentistry offers an international, peer reviewed and open access platform for publishing recent advances in the field of dental and allied sciences for the benefit of clinicians, other fellow researchers, industrialists and academicians. it covers oral disorders and medicine, oral radiology, oral a... Read More

Journal of Diabetes and Metabolism Honors the Editors for Achieving Excellence in Journal Mentorship on the Occasion of 10th Anniversary

Image On the grand occasion of 10th anniversary, Journal of Diabetes and Metabolism (eISSN: 2155-6156) expresses gratitude to all its elite panel of editorial board members for their continuous efforts, support and encouragement throughout the publication journey of the journal, right from its inception in the year 2010 and congratulates them for making the journal achieve its goals and ... Read More

Biology and Medicine Celebrates More Than a Decade of Medical Research Publication with Granduer and Dedication

Image Biology and Medicine, an international peer-reviewed journal celebrates more than a decade of its existence in the field of medical and biological research. Journal extends a very warm welcome to all the authors, researchers, editors and students to contribute their latest research findings as full length articles to this collaborative medical journal. The journal is committed to serve its readers, and authors are encouraged to articulate their novel ideas, opinions, comments, different perspective or analysis of the e... Read More