Pharmaceutics and Novel Drug Delivery Systems
Journal of Drug Designing: Open Access is using online manuscript submission, review and tracking systems of Longdom Publishing SL for quality and quick review processing.
Longdom Publishing SL is using Online Review and Editorial Tracking Systems for quality review process. Editorial Managerial System is an online submission and review system, where authors can submit manuscripts and track their progress. Reviewers can download manuscripts and submit their opinions. Editors can... Read More
Journal of 
Journal of Developing Drugs, a peer reviewed, Open Access Journal provides an open platform for eminent scientists around the globe to publish their scholarly work in field related to Drugs. Various regulatory approaches for toxic chemicals management are included in scope of Journal of Developing Drugs.
Journal of Developing Drugs is an open access, peer reviewed international journal with a primary objective to provide research and applications related to Pharmaceutical & Toxicology Sciences.
The Journal deals with surgery, internal medicine, ca... 
T Cell-Dependent in situ Initiation and Systemic Regulation Model ofImmune Responses
Hypothesis: A peripheral initiation and systemic response model of immunity.Very few antigen presenting cells (APCs) are able to elicit an immuneresponse. We suggest, that peripheral immune activation, e.g. via theskin, may induce parallel co-migration of dendritic cells (DC’s) andactivated antigen-specific T cells to the draining lymph nodes andbeyond. Herewith, memory-like anti-foreign-reactive T cells inaddition or even superior to naïve T cells once... 
Androgen Receptor as Prognostic Marker in Triple-Negative Breast Cancer Patients
Purpose: The purpose of this study was to assess the prognostic impact of androgen receptor (AR) expression in patients with triple-negative breast cancer (TNBC).
Methods/patients: 101 patients treated for primary TNBC without distant metastasis from 1999 to 2015 were identified from breast surgery database. Kaplan-Meier and Cox regression models evaluated disease-free survival (DFS) and overall survival (OS).
Results:... 
Objective: Phytochemical constituents of herbal extracts has shown positive response of antioxidant activity. The purpose of the present study was to investigate the antioxidant activity of polyphenolic flavonoids in the ethanolic extract of stem of Nicotiana tabacum.
Materials and Methods: Flavonoids contents were determined by both thin layer chromatography and aluminium chloride colorimetric method, where as phenolic content was determine by Folin-Ciocalteau method. Antioxidant activity was observed by determin... 
Lentinan Exerts its Anti-Inflammatory Activity by Suppressing TNFR1 Transfer to the Surface of Intestinal Epithelial Cells through Dectin-1 in an in vitro and mice model
It has been reported that lentinan, β-1,3; 1,6-glucan derived from Lentinula edodes, suppresses intestinal inflammation and ameliorates symptoms of colitis. However, the mechanism of intestinal anti-inflammatory activity of lentinan and how it is recognized by intestinal epithelial cells remains largely unclear. The receptor for lentinan on intestinal epithelial cells was identified using an ... 
Developing Electronic-nose Technologies for Clinical Practice
The development of relatively simple gas-sensing devices with sensor arrays capable of constructing molecular profiles of complex Volatile Organic Compound (VOC) metabolites from clinical samples, based on production of healthy or disease-specific digital signature patterns, may soon help to revolutionize diagnostic procedures in clinical practice. This mini-review summarizes the development of recent portable electronic-nose (e-nose) technologies as new diagnostic tools with the potential for accelerat... 
The Journal 
Commentary on “Gallbladder Cancer: South American Experience
When I was invited by Dr. Ghassan Abou-Alfa to write an article about the South American experience in gallbladder cancer (GC) I felt enthusiasm. It was an opportunity to make a contribution to this public health problem. GC is among the leading causes of death from cancer in women in many Western areas in my country Argentina and in South America. Based on their daily practice experience many health workers in Salta, the province where I live at the northwest of Argentina, know that GC is a loc... 
MicroRNAs in Skin Biology: Biogenesis, Regulations and Functions in Homeostasis and Diseases
The progression in science gives novel and deeper understandings of human beings organisms. The Human Genome Project uncovered about 20,500 human genes. More recently, non-coding RNAs saw the light and gained researchers interest. Among the different subsets of these non-coding RNAs, microRNAs were identified as 18-25 nucleotides long and have been shown to play critical regulatory roles in a wide range of cellular processes. Emerging studies highlighted the importance of ... 
Parathyroid Carcinoma has a PD-L1 Expression, and Share with Atypical Neoplasms an Abundant Intratumoral Macrophagic
Aim: The aim of this study was characterized programmed death-ligand 1 (PD-L1) expression and tumoralinfiltrating lymphocytes (TILs) in parathyroid carcinoma (PC) and atypical parathyroid neoplasms (ANs).
Methods: Our tissue samples constitute 30 parathyroid tumors (17 PC and 13 ANs) which were available from a prospectively collected database at the University of Texas M.D Anderson Cancer Center from 1... 
The team “
The Journal, 
Journal of Developing Drugs is a peer-reviewed Journal, encourages on-going international research and information exchange through publication of latest advances.
The Journal is pleased to inform that it is been running successfully since 8 years and is running towards its 9th Anniversary. It is an Open access scholarly Developing Drugs journal with an ISSN No: 2329-6631. This journal is known for its quality research articles in the field of Pharmaceutics, Nanotechnology, Novel Drug Delivery Systems, Quality Control, Quality Assurance, International Regulatory, ... 
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Journal of 
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The perspective of the 
Journal of Developing Drugs is an open access Scientific Journal which mainly focuses on articles of Drug designing. The 
Scope of Drug Designing: Open Access Journal
Statistical Designs for Pharmaceutical
Risk Factors for Febrile Seizures in Children
Objective: we aimed to identify the factors associated with febrile seizures (FS) occurrence.
Methods: This was a case-control study. Sixty cases of FS were prospectively recorded and compared to 60 controls admitted for fever without seizures. Baseline Data were collected from all consecutive patients and laboratory hematological parameters including complete blood count, serum iron, serum ferritin and zinc levels were perform... 
The Presence of Autonomous and Non-Autonomous Replication in Cancer and their Connection through Inflammation
Targeted therapy with small molecule such as TKI (tyrosine kinase inhibitor) against EGFR has achieved high response rate and significant clinical benefits in selected group of lung cancer patients in the past decade. One reliable criterion for patient selection is the presence of certain mutations in the EGFR gene such as mutations in exon-19, 20 or 21 in lung cancer patients. In these patients, it is often observed that TKI therapy could be so effective ... 
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Special Issue on Drug Designing : Edited by Guest Editors
The 
Pemphigus Herpetiformis with Only Positive Anti-Envoplakin Antibodies
Pemphigus herpetiformis, first described in 1975, is a rare subtype of autoimmune bullous disease that associates clinical features of dermatitis herpetiformis with immunological features of pemphigus. We present a 48-years-old female patient, with pruritic lesions located mainly in the upper limbs with 6 years of evolution. Physical examination revealed erythematous papules, some excoriated and vesicles of translucent content distributed on her arms, trunk and neck. Histological examination of ... 
Autoimmune Hemolytic Anemia and Thrombocytopenia with Tuberculous Lymphadenitis
Well-differentiated small-intestinal neuroendocrine tumors (SI-NETs) tend to be biologically indolent.Despite this tendency, they have a predilection for metastasis. Peritoneal involvement is quite common as isunfortunately peritoneal carcinomatosis (PC). PC is a dreaded metastatic complication due to the significant morbidity it creates for patients as well as well as increasing their mortality risk. The risk factors for PC development in SI-NETs remain understudied; however, on... 
Journal of Drug Designing: Open Access | Celebrating 9th Anniversary
Journal of Biology and Todays World is a perfect Insight for the readers related to Biology and Medicine. It has a vast scope and is currently running since 8 years with many successful quality articles published. Due its broad scope, a diverse set of topics, such as genetics, biotechnology, biochemistry, microbiology, cellular & molecular biology, and disease biology, are covered under the aegis of this journal. Additionally, the journal also provides rapid, authoritative, and insightful reports and interpretation of topical and future trends in science.
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Highlights on Drug Designing
The Journal, 
Reviewing the progression in Drug Designing research
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Pathology: A big innovation to medicine
Journal of Medical and Surgical Pathology (JMSP) has announced almost 20 percent discount on article processing charge to commemorate its 4th Anniversary.
The Editorial Board of Journal of Medical and Surgical Pathology is overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal and take part in the 4th anniversary celebrations. During this year we look forward to taking some initiatives that would encourage and rewar... 
On behalf of the Journal of Developing Drugs, as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been ten long years we have started the Journal, now we are celebrating the 
Alopecia is not a well-known adverse effect of second-line anti-tuberculosis drugs. It is, however, been frequently reported in Eritrea and 83% of the reports of alopecia associated with second-line anti-TB drugs in the global adverse drug reaction database, as of July 25, 2017, were submitted from Eritrea. It is wondering why this much variation is happening and this study is therefore aimed at quantifying the risk, identifying possible risk factors and elucidating the causal association between alopecia and the second-line anti-TB drugs in Eritrea. This was an observational cohort study o... 
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